Orbimed Advisors Llc - Insider Trading & Ownership

Location
601 Lexington Avenue, 54 Th Floor, New York, NY
Summary
The estimated value of insider holdings of Orbimed Advisors Llc is at least $862M dollars as of November 26, 2025. Orbimed Advisors Llc is the 10%+ Owner of SpringWorks Therapeutics, Inc. and owns shares of SpringWorks Therapeutics, Inc. (SWTX) stock worth about $233M. Orbimed Advisors Llc is the Director, 10%+ Owner of Enliven Therapeutics, Inc. and owns shares of Enliven Therapeutics, Inc. (ELVN) stock worth about $170M. Orbimed Advisors Llc is the Director of Sionna Therapeutics, Inc. and owns shares of Sionna Therapeutics, Inc. (SION) stock worth about $160M. Orbimed Advisors Llc is the Director, 10%+ Owner of Third Harmonic Bio, Inc. and owns shares of Third Harmonic Bio, Inc. (THRD) stock worth about $59.5M. Orbimed Advisors Llc is the 10%+ Owner of NeuroPace Inc and owns shares of NeuroPace Inc (NPCE) stock worth about $51.6M. Orbimed Advisors Llc is the Director, 10%+ Owner of Prelude Therapeutics Inc and owns shares of Prelude Therapeutics Inc (PRLD) stock worth about $38.2M. Orbimed Advisors Llc is the Director, 10%+ Owner of Corvus Pharmaceuticals, Inc. and owns shares of Corvus Pharmaceuticals, Inc. (CRVS) stock worth about $29.8M. Orbimed Advisors Llc is the 10%+ Owner of 89bio, Inc. and owns shares of 89bio, Inc. (ETNB) stock worth about $21.1M. Orbimed Advisors Llc is the 10%+ Owner of TELA Bio, Inc. and owns shares of TELA Bio, Inc. (TELA) stock worth about $10.9M. Orbimed Advisors Llc is the Director of Venetian-1 Acquisition Corp. and owns shares of Lomond Therapeutics Holdings, Inc. stock worth about $10.7M. Orbimed Advisors Llc is the Director of Disc Medicine, Inc. and owns shares of Disc Medicine, Inc. (IRON) stock worth about $10.1M. Orbimed Advisors Llc is the Director, 10%+ Owner of Edgewise Therapeutics, Inc. and owns shares of Edgewise Therapeutics, Inc. (EWTX) stock worth about $8.93M. Orbimed Advisors Llc is the Director, 10%+ Owner of MBX Biosciences, Inc. and owns shares of MBX Biosciences, Inc. (MBX) stock worth about $8.11M. Orbimed Advisors Llc is the 10%+ Owner of PMV Pharmaceuticals, Inc. and owns shares of PMV Pharmaceuticals, Inc. (PMVP) stock worth about $7.56M. Orbimed Advisors Llc is the Director, 10%+ Owner of Terns Pharmaceuticals, Inc. and owns shares of Terns Pharmaceuticals, Inc. (TERN) stock worth about $7.56M. Orbimed Advisors Llc is the Director of Verona Pharma plc and owns shares of Verona Pharma plc (VRNA) stock worth about $7.46M. Orbimed Advisors Llc is the Director, 10%+ Owner of ArriVent Biopharma, Inc. and owns shares of ArriVent BioPharma, Inc. (AVBP) stock worth about $5.52M. Orbimed Advisors Llc is the Director of Keros Therapeutics, Inc. and owns shares of Keros Therapeutics, Inc. (KROS) stock worth about $5.26M. Orbimed Advisors Llc is the 10%+ Owner of Adicet Bio, Inc. and owns shares of Adicet Bio, Inc. (ACET) stock worth about $4.49M. Orbimed Advisors Llc is the Director, 10%+ Owner of Acutus Medical, Inc. and owns shares of Acutus Medical, Inc. (AFIB) stock worth about $2.62M. Orbimed Advisors Llc is the 10%+ Owner of Passage BIO, Inc. and owns shares of Passage BIO, Inc. (PASG) stock worth about $2M. Orbimed Advisors Llc is the 10%+ Owner of Arcutis Biotherapeutics, Inc. and owns shares of Arcutis Biotherapeutics, Inc. (ARQT) stock worth about $1.47M. Orbimed Advisors Llc is the Director of Janux Therapeutics, Inc. and owns shares of Janux Therapeutics, Inc. (JANX) stock worth about $1.36M. Orbimed Advisors Llc is the Director, 10%+ Owner of Homology Medicines, Inc. and owns shares of Q32 Bio Inc. (QTTB) stock worth about $1.29M. Orbimed Advisors Llc is the 10%+ Owner of Galecto, Inc. and owns shares of Galecto, Inc. (GLTO) stock worth about $1.13M. Orbimed Advisors Llc is the 10%+ Owner of scPharmaceuticals Inc. and owns shares of scPharmaceuticals Inc. (SCPH) stock worth about $1.01M. Orbimed Advisors Llc is the Director of Shattuck Labs, Inc. and owns shares of Shattuck Labs, Inc. (STTK) stock worth about $912K. Orbimed Advisors Llc is the Director of ImageneBio, Inc. and owns shares of Ikena Oncology, Inc. (IKNA) stock worth about $717K. Orbimed Advisors Llc is the 10%+ Owner of Traws Pharma, Inc. and owns shares of Traws Pharma, Inc. (TRAW) stock worth about $283K. Orbimed Advisors Llc is the Director of Repare Therapeutics Inc. and owns shares of Repare Therapeutics Inc. (RPTX) stock worth about $233K.
Signature
/s/ Carl L. Gordon, Member of OrbiMed Advisors LLC
All Insider Reports
All Insider Reports

Ownership of Orbimed Advisors Llc

Symbol Company Relationship Holdings Value Past Year Net Change Change % Report Period
SWTX SpringWorks Therapeutics, Inc. 10%+ Owner $233M Sep 12, 2022
ELVN, IMRA Enliven Therapeutics, Inc. Director, 10%+ Owner $170M May 16, 2024
SION Sionna Therapeutics, Inc. Director $160M -$4.81M -2.92% Nov 24, 2025
THRD Third Harmonic Bio, Inc. Director, 10%+ Owner $59.5M Sep 19, 2022
NPCE NeuroPace Inc 10%+ Owner $51.6M -$2.67M -4.91% May 14, 2025
PRLD Prelude Therapeutics Inc Director, 10%+ Owner $38.2M May 22, 2023
CRVS Corvus Pharmaceuticals, Inc. Director, 10%+ Owner $29.8M -$4.89M -14.1% Jun 27, 2025
ETNB 89bio, Inc. 10%+ Owner $21.1M Jan 25, 2022
TELA TELA Bio, Inc. 10%+ Owner $10.9M Jun 28, 2024
NONE Lomond Therapeutics Holdings, Inc. Director $10.7M Nov 1, 2024
IRON Disc Medicine, Inc. Director $10.1M -$20.1M -66.6% Mar 24, 2025
EWTX Edgewise Therapeutics, Inc. Director, 10%+ Owner $8.93M +$10M Apr 3, 2025
MBX MBX Biosciences, Inc. Director, 10%+ Owner $8.11M +$2.02M +33.2% Feb 14, 2025
PMVP PMV Pharmaceuticals, Inc. 10%+ Owner $7.56M -$2.42M -24.2% Oct 23, 2025
TERN Terns Pharmaceuticals, Inc. Director, 10%+ Owner $7.56M Jul 15, 2024
VRNA Verona Pharma plc Director $7.46M May 11, 2023
AVBP ArriVent BioPharma, Inc. Director, 10%+ Owner $5.52M Jan 30, 2024
KROS Keros Therapeutics, Inc. Director $5.26M Aug 13, 2024
ACET Adicet Bio, Inc. 10%+ Owner $4.49M +$5M Oct 8, 2025
AFIB Acutus Medical, Inc. Director, 10%+ Owner $2.62M Jul 19, 2021
PASG Passage BIO, Inc. 10%+ Owner $2M -$839K -29.5% Jun 24, 2025
ARQT Arcutis Biotherapeutics, Inc. 10%+ Owner $1.47M Jun 24, 2022
JANX Janux Therapeutics, Inc. Director $1.36M Dec 29, 2021
QTTB Q32 Bio Inc. Director, 10%+ Owner $1.29M Mar 25, 2024
GLTO Galecto, Inc. 10%+ Owner $1.13M Aug 15, 2023
SCPH scPharmaceuticals Inc. 10%+ Owner $1.01M Aug 13, 2024
STTK Shattuck Labs, Inc. Director $912K +$5.47M Aug 25, 2025
IKNA Ikena Oncology, Inc. Director $717K Jul 25, 2025
TRAW Traws Pharma, Inc. 10%+ Owner $283K Dec 29, 2024
RPTX Repare Therapeutics Inc. Director $233K Sep 3, 2021
ALPN ALPINE IMMUNE SCIENCES, INC. Director $0 May 18, 2024
SPRY ARS Pharmaceuticals, Inc. Director $0 Aug 26, 2024
CMPX Compass Therapeutics, Inc. Director, 10%+ Owner $0 -$5.68M -100% Apr 9, 2025
KNTE Kinnate Biopharma Inc. Director, 10%+ Owner $0 Apr 3, 2024
THRX Theseus Pharmaceuticals, Inc. Director, 10%+ Owner $0 Feb 14, 2024
TSBX Turnstone Biologics Corp. Director $0 Aug 8, 2025
XTNT Xtant Medical Holdings, Inc. 10%+ Owner $0 -$30.7M -100% Apr 10, 2025
SRRA Sierra Oncology, Inc. Director, 10%+ Owner Jul 1, 2022
TCDA Tricida, Inc. Director, 10%+ Owner Nov 22, 2022
UPB Upstream Bio, Inc. Director, 10%+ Owner Oct 15, 2024

Insider Transactions Reported by Orbimed Advisors Llc:

Sym Company Class Transaction % Value $ * Price $ Shares Shares After Date Ownership
* An asterisk sign (*) next to the price indicates that the price is likely invalid.