| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 19.99% | +36.6% | $21M | $14.7M | 11.9M | +233% | BEHZAD AGHAZADEH | Feb 28, 2025 |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 9.99% | $8.31M | 4.73M | SUVRETTA CAPITAL MANAGEMENT, LLC | Mar 4, 2025 | |||
| ABG Management Ltd. | 6.3% | $5.13M | 2.91M | Fan Yu | Mar 4, 2025 | |||
| BML Investment Partners, L.P. | 4.98% | -49.2% | $4.28M | -$255K | 2.44M | 0% | Leonard Braden Michael | Mar 5, 2025 |
| QVT Financial LP | 9.37% | $4.07M | 2.31M | QVT Financial LP | Dec 31, 2024 | |||
| Desai Neil | 4.9% | -47.8% | $4M | $16.5K | 2.27M | +0.41% | Neil Desai | Mar 4, 2025 |
| ACUTA CAPITAL PARTNERS, LLC | 7.8% | $3.38M | 1.92M | Anupam Dalal | Dec 19, 2024 | |||
| Point72 Asset Management, L.P. | 6% | $2.59M | 1.47M | Point72 Asset Management, L.P. | Jan 22, 2025 | |||
| EcoR1 Capital, LLC | 1.4% | $607K | 345K | EcoR1 Capital, LLC | Dec 31, 2024 | |||
| Satter Muneer A | 0% | $1.16K | 659 | Satter Muneer A | Dec 31, 2024 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q1 | 36.8K | $65K | -$136K | $1.76 | 2 |
| 2024 Q4 | 15M | $47.2M | +$5.01M | $3.16 | 51 |
| 2024 Q3 | 12M | $24.7M | +$1.83M | $2.06 | 51 |
| 2024 Q2 | 11.5M | $16.7M | -$3.33M | $1.46 | 62 |
| 2024 Q1 | 13.2M | $30.9M | +$1.32M | $2.34 | 59 |
| 2023 Q4 | 12.8M | $25.8M | -$10.7M | $2.02 | 61 |
| 2023 Q3 | 14.2M | $68.8M | +$1.72M | $4.84 | 68 |
| 2023 Q2 | 13.8M | $94.2M | -$902K | $6.84 | 64 |
| 2023 Q1 | 13.8M | $100M | -$16.8M | $7.24 | 68 |
| 2022 Q4 | 15.3M | $192M | +$3.02M | $12.83 | 74 |
| 2022 Q3 | 15M | $212M | +$32.8M | $14.13 | 65 |
| 2022 Q2 | 12.8M | $158M | +$4.29M | $12.32 | 64 |
| 2022 Q1 | 12.5M | $213M | -$7.7M | $16.97 | 50 |
| 2021 Q4 | 12.2M | $294M | +$23.9M | $24.15 | 42 |
| 2021 Q3 | 11.1M | $324M | +$324M | $29.37 | 30 |