| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| FEDERATED HERMES, INC. | 11% | -39% | $55,463,739 | -$21,682,577 | 10,544,437 | -28% | Federated Hermes, Inc. | 30 Sep 2025 |
| BlackRock, Inc. | 6.5% | $18,674,083 | 5,763,606 | BlackRock, Inc. | 30 Jun 2025 | |||
| VANGUARD GROUP INC | 5.2% | $15,082,356 | 4,655,048 | The Vanguard Group | 30 Jun 2025 | |||
| Point72 Asset Management, L.P. | 3.2% | $8,109,259 | 2,845,354 | Point72 Asset Management, L.P. | 31 Mar 2025 |
As of 30 Sep 2025, 98 institutional investors reported holding 60,876,849 shares of aTYR PHARMA INC - COMMON STOCK (ATYR). This represents 62% of the company’s total 97,996,626 outstanding shares.
The largest institutional shareholders of aTYR PHARMA INC - COMMON STOCK (ATYR) together control 59% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 15% | 14,697,995 | +10% | 0% | $10,603,134 |
| FEDERATED HERMES, INC. | 11% | 10,544,437 | -28% | 0.01% | $7,606,757 |
| BlackRock, Inc. | 6.6% | 6,473,884 | +12% | 0% | $4,670,259 |
| VANGUARD GROUP INC | 5.7% | 5,630,935 | +21% | 0% | $4,059,904 |
| UBS Group AG | 4.6% | 4,505,955 | +158% | 0% | $3,248,793 |
| STATE STREET CORP | 4.3% | 4,196,166 | +238% | 0% | $3,027,114 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.2% | 2,178,203 | +3.8% | 0% | $1,571,682 |
| MILLENNIUM MANAGEMENT LLC | 1.9% | 1,890,921 | +18% | 0% | $1,364,110 |
| MORGAN STANLEY | 0.72% | 710,341 | +173% | 0% | $512,440 |
| GSA CAPITAL PARTNERS LLP | 0.72% | 706,731 | +42% | 0.04% | $510,000 |
| GOLDMAN SACHS GROUP INC | 0.7% | 688,165 | +1797% | 0% | $496,443 |
| NORTHERN TRUST CORP | 0.69% | 674,122 | -1% | 0% | $486,312 |
| TANG CAPITAL MANAGEMENT LLC | 0.68% | 671,134 | 0% | 0.02% | $484,156 |
| Tikvah Management LLC | 0.47% | 460,833 | -81% | 0.1% | $332,445 |
| STATE OF WISCONSIN INVESTMENT BOARD | 0.45% | 438,262 | 0% | $316,162 | |
| Ensign Peak Advisors, Inc | 0.42% | 414,732 | +76% | 0% | $299,188 |
| Artia Global Partners LP | 0.38% | 372,276 | 0.05% | $268,560 | |
| BARCLAYS PLC | 0.35% | 341,359 | +15% | 0% | $246,257 |
| XTX Topco Ltd | 0.32% | 312,410 | 0.01% | $225,373 | |
| WELLINGTON MANAGEMENT GROUP LLP | 0.3% | 289,231 | +35% | 0% | $208,651 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.27% | 261,043 | +0.96% | 0% | $188,316 |
| FLPUTNAM INVESTMENT MANAGEMENT CO | 0.24% | 235,255 | +466% | 0% | $169,713 |
| Brevan Howard Capital Management LP | 0.24% | 234,613 | 0% | $168,922 | |
| Nuveen, LLC | 0.23% | 227,941 | +17% | 0% | $164,436 |
| JANE STREET GROUP, LLC | 0.23% | 227,785 | +525% | 0% | $164,324 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 45,332 | $34,921 | -$11,632 | $0.78 | 4 |
| 2025 Q3 | 60,876,849 | $43,917,863 | -$49,484,419 | $0.72 | 98 |
| 2025 Q2 | 66,359,568 | $336,444,770 | +$26,875,817 | $5.07 | 109 |
| 2025 Q1 | 61,756,683 | $186,507,450 | +$18,904,934 | $3.02 | 86 |
| 2024 Q4 | 54,865,656 | $198,612,160 | +$28,551,641 | $3.62 | 77 |
| 2024 Q3 | 47,854,177 | $84,222,647 | -$407,421 | $1.76 | 54 |
| 2024 Q2 | 48,123,448 | $75,072,910 | +$8,931,063 | $1.56 | 45 |
| 2024 Q1 | 41,805,838 | $81,517,658 | +$1,475,515 | $1.95 | 56 |
| 2023 Q4 | 41,213,560 | $58,107,233 | +$3,551,996 | $1.41 | 45 |
| 2023 Q3 | 37,131,978 | $58,669,207 | +$2,049,115 | $1.58 | 41 |
| 2023 Q2 | 35,668,257 | $77,043,513 | +$2,315,557 | $2.16 | 41 |
| 2023 Q1 | 34,663,995 | $72,793,910 | +$35,336,607 | $2.10 | 37 |
| 2022 Q4 | 18,353,120 | $40,192,707 | -$2,084,850 | $2.19 | 35 |
| 2022 Q3 | 19,009,787 | $57,028,570 | +$782,323 | $3.00 | 31 |
| 2022 Q2 | 18,767,627 | $53,115,149 | -$3,103,801 | $2.83 | 35 |
| 2022 Q1 | 19,627,491 | $105,008,778 | -$6,161,774 | $5.35 | 38 |
| 2021 Q4 | 20,534,388 | $153,393,033 | +$3,923,414 | $7.47 | 45 |
| 2021 Q3 | 18,824,963 | $170,928,000 | +$109,402,310 | $9.08 | 39 |
| 2021 Q2 | 6,787,411 | $33,118,000 | +$4,920,158 | $4.88 | 23 |
| 2021 Q1 | 5,779,531 | $25,721,000 | +$195,254 | $4.45 | 19 |
| 2020 Q4 | 5,760,740 | $22,351,000 | -$373,364 | $3.88 | 18 |
| 2020 Q3 | 5,633,800 | $18,195,000 | +$464,498 | $3.23 | 19 |
| 2020 Q2 | 5,472,169 | $24,295,000 | +$1,598,380 | $4.44 | 21 |
| 2020 Q1 | 5,114,483 | $14,319,000 | +$9,326,718 | $2.80 | 21 |
| 2019 Q4 | 1,793,570 | $7,478,000 | +$296,912 | $4.17 | 13 |
| 2019 Q3 | 1,718,322 | $6,014,000 | +$4,151,946 | $3.50 | 13 |
| 2019 Q2 | 530,377 | $193,000 | +$193,000 | $0.36 | 5 |