Type / Class
Equity / Common Stock, $0.0001 par value
Shares outstanding
81,149,970
Total 13F shares
63,624,754
Share change
+1,349,292
Total reported value
$952,552,077
Put/Call ratio
57%
Price per share
$14.97
Number of holders
128
Value change
+$19,485,363
Number of buys
80
Number of sells
42

Institutional Holders of Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value (SYRE) as of Q2 2025

As of 30 Jun 2025, Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value (SYRE) was held by 128 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 63,624,754 shares. The largest 10 holders included FMR LLC, Fairmount Funds Management LLC, BlackRock, Inc., RTW INVESTMENTS, LP, TANG CAPITAL MANAGEMENT LLC, VANGUARD GROUP INC, VR ADVISER, LLC, BRAIDWELL LP, Capital International Investors, and Driehaus Capital Management LLC. This page lists 128 institutional shareholders reporting positions in this security for the Q2 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.