Type / Class
Equity / Common Stock, $0.0001 par value
Shares outstanding
81,149,970
Total 13F shares
46,514
Share change
+23,465
Total reported value
$1,524,082
Price per share
$32.76
Number of holders
4
Value change
+$768,996
Number of buys
2

Institutional Holders of Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value (SYRE) as of Q4 2025

As of 31 Dec 2025, Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value (SYRE) was held by 4 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 46,514 shares. The largest 4 holders included SG Americas Securities, LLC, Assenagon Asset Management S.A., NISA INVESTMENT ADVISORS, LLC, and GAMMA Investing LLC. This page lists 4 institutional shareholders reporting positions in this security for the Q4 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.