| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Sarissa Capital Management LP | 8.1% | $15,061,500 | 33,470,000 | Sarissa Capital Management LP | 25 Mar 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (% of par) | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 7 | $115 | -$285,709 | 1,640.44% | 1 |
| 2025 Q2 | 19,160 | $285,822 | -$34,901,936 | 1,622.09% | 4 |
| 2025 Q1 | 67,596,304 | $30,275,436 | -$786,941 | 44.81% | 127 |
| 2024 Q4 | 70,840,892 | $34,386,789 | +$2,447,589 | 48.5% | 157 |
| 2024 Q3 | 65,472,406 | $41,052,398 | -$8,167,451 | 62.69% | 156 |
| 2024 Q2 | 77,787,203 | $53,525,417 | -$8,049,987 | 68.8% | 168 |
| 2024 Q1 | 88,266,465 | $78,618,746 | -$3,228,550 | 89.08% | 170 |
| 2023 Q4 | 40,073 | $34,864 | -$26,864 | 87% | 3 |
| 2023 Q3 | 90,066,863 | $82,797,674 | -$12,629,261 | 92% | 177 |
| 2023 Q2 | 102,936,849 | $122,480,987 | +$4,289,867 | 119% | 192 |
| 2023 Q1 | 98,953,159 | $148,394,010 | -$17,776,403 | 150% | 193 |
| 2022 Q4 | 111,853,996 | $135,327,003 | -$15,427,127 | 121% | 189 |
| 2022 Q3 | 128,652,342 | $140,309,678 | -$11,045,189 | 108.99% | 164 |
| 2022 Q2 | 135,188,482 | $201,414,203 | -$6,706,495 | 149% | 188 |
| 2022 Q1 | 131,849,371 | $433,823,669 | -$13,336,923 | 328.97% | 201 |
| 2021 Q4 | 135,121,339 | $455,340,758 | +$43,786,763 | 337% | 212 |
| 2021 Q3 | 119,684,942 | $610,361,310 | -$30,358,221 | 510% | 224 |
| 2021 Q2 | 128,042,126 | $560,872,091 | -$63,956,482 | 438% | 222 |
| 2021 Q1 | 138,393,634 | $859,192,019 | -$59,136,874 | 620.99% | 236 |
| 2020 Q4 | 148,190,178 | $724,691,294 | +$20,389,286 | 489% | 214 |
| 2020 Q3 | 146,559,360 | $616,669,102 | -$82,505,420 | 420.98% | 239 |
| 2020 Q2 | 162,070,481 | $1,121,443,111 | +$17,952,981 | 691.99% | 262 |
| 2020 Q1 | 167,073,214 | $668,297,031 | -$308,369,302 | 400% | 267 |
| 2019 Q4 | 164,271,375 | $3,521,796,294 | -$505,865,506 | 2,144% | 314 |
| 2019 Q3 | 188,428,829 | $2,856,637,711 | +$335,410,468 | 1,515.99% | 268 |
| 2019 Q2 | 162,818,786 | $3,156,841,785 | +$259,522,731 | 1,938.98% | 247 |
| 2019 Q1 | 157,126,707 | $3,260,845,677 | +$69,427,833 | 2,076% | 242 |
| 2018 Q4 | 155,995,013 | $2,121,209,514 | +$187,695,609 | 1,361% | 223 |
| 2018 Q3 | 138,677,530 | $2,256,274,378 | +$552,646,670 | 1,627% | 155 |
| 2018 Q2 | 111,871,330 | $345,619,213 | -$38,017,586 | 309% | 118 |
| 2018 Q1 | 124,281,942 | $374,078,488 | +$27,484,716 | 300.99% | 120 |
| 2017 Q4 | 111,495,254 | $447,099,818 | +$13,314,528 | 400.95% | 115 |
| 2017 Q3 | 108,685,739 | $380,355,236 | +$21,302,373 | 350% | 107 |
| 2017 Q2 | 102,263,102 | $412,106,502 | -$532,770 | 402.98% | 107 |
| 2017 Q1 | 101,729,470 | $325,524,236 | +$1,271,904 | 320% | 102 |
| 2016 Q4 | 105,406,586 | $324,635,988 | -$3,611,000 | 307.97% | 102 |
| 2016 Q3 | 106,214,762 | $338,816,200 | +$218,988,691 | 319% | 97 |
| 2016 Q2 | 37,775,400 | $81,590,184 | -$5,302,340 | 216% | 79 |
| 2016 Q1 | 40,929,471 | $62,613,950 | -$10,200,349 | 152.98% | 72 |
| 2015 Q4 | 47,202,763 | $89,210,350 | -$2,458,322 | 189% | 75 |
| 2015 Q3 | 48,759,772 | $94,107,965 | -$9,195,298 | 193% | 65 |
| 2015 Q2 | 50,778,744 | $124,753,098 | +$15,327,660 | 246% | 72 |
| 2015 Q1 | 44,229,124 | $103,422,537 | -$4,546,196 | 234% | 80 |
| 2014 Q4 | 49,481,949 | $48,426,255 | -$13,598,657 | 98% | 64 |
| 2014 Q3 | 61,702,462 | $67,240,621 | +$3,368,104 | 109% | 76 |
| 2014 Q2 | 54,959,262 | $96,647,259 | +$909,318 | 176% | 76 |
| 2014 Q1 | 53,744,256 | $97,259,149 | +$12,291,402 | 181% | 85 |