| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| FMR LLC | 15% | $273,383,018 | 6,907,100 | FMR LLC | 30 Jun 2025 | |||
| Fairmount Funds Management LLC | 10% | $229,546,677 | 5,776,881 | Peter Evan Harwin | 10 Oct 2025 | |||
| WELLINGTON MANAGEMENT GROUP LLP | 11% | +29% | $193,354,079 | +$42,724,077 | 4,885,146 | +28% | Wellington Management Group LLP | 31 Jul 2025 |
| RTW INVESTMENTS, LP | 6% | $86,244,685 | 2,712,097 | RTW Investments, LP | 31 Dec 2024 | |||
| BlackRock, Inc. | 5.5% | $99,691,136 | 2,518,725 | BlackRock, Inc. | 30 Jun 2025 | |||
| DRIEHAUS CAPITAL MANAGEMENT LLC | 4.7% | $85,757,284 | 2,158,502 | DRIEHAUS CAPITAL MANAGEMENT LLC | 30 Sep 2025 |
As of 30 Sep 2025, 172 institutional investors reported holding 59,584,018 shares of Apogee Therapeutics, Inc. - Common Stock (APGE). This represents 129% of the company’s total 46,121,838 outstanding shares.
The largest institutional shareholders of Apogee Therapeutics, Inc. - Common Stock (APGE) together control 107% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| VR ADVISER, LLC | 18% | 8,493,321 | 0% | 19% | $337,439,643 |
| FMR LLC | 15% | 6,916,462 | +0.14% | 0.01% | $274,791,036 |
| WELLINGTON MANAGEMENT GROUP LLP | 10% | 4,723,701 | +24% | 0.03% | $187,672,640 |
| RTW INVESTMENTS, LP | 5.9% | 2,712,097 | 0% | 1.3% | $107,751,614 |
| BlackRock, Inc. | 5.8% | 2,686,026 | +4.8% | 0% | $106,715,814 |
| VANGUARD GROUP INC | 4.9% | 2,245,631 | +6.5% | 0% | $89,218,920 |
| Driehaus Capital Management LLC | 4.7% | 2,158,502 | -6.6% | 0.61% | $85,757,284 |
| Fairmount Funds Management LLC | 4.4% | 2,048,647 | 0% | 7.3% | $81,392,745 |
| STATE STREET CORP | 3.6% | 1,655,548 | +31% | 0% | $65,774,922 |
| Paradigm Biocapital Advisors LP | 3.3% | 1,521,757 | +59% | 1.8% | $60,459,406 |
| BRAIDWELL LP | 3.1% | 1,438,745 | -2.7% | 1.7% | $57,161,339 |
| ALLIANCEBERNSTEIN L.P. | 3.1% | 1,419,132 | +2.2% | 0.02% | $56,382,114 |
| PERCEPTIVE ADVISORS LLC | 2.9% | 1,351,989 | +14% | 1.6% | $53,714,523 |
| Affinity Asset Advisors, LLC | 2.5% | 1,173,426 | +70% | 4.3% | $46,620,215 |
| CITADEL ADVISORS LLC | 2.5% | 1,169,244 | +136% | 0.04% | $46,454,065 |
| JPMORGAN CHASE & CO | 2.5% | 1,137,731 | +1.1% | 0% | $45,202,052 |
| MERCER GLOBAL ADVISORS INC /ADV | 2.1% | 970,581 | +18% | 0.06% | $38,561,183 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.9% | 892,203 | +14% | 0% | $35,453,920 |
| UBS Group AG | 1.7% | 799,465 | +646% | 0.01% | $31,762,745 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.6% | 750,529 | -1.4% | 0% | $29,820,000 |
| FRANKLIN RESOURCES INC | 1.6% | 730,761 | -14% | 0.01% | $29,033,130 |
| BARCLAYS PLC | 1.4% | 642,316 | +5.5% | 0.01% | $25,519,215 |
| GOLDMAN SACHS GROUP INC | 1.3% | 599,616 | -9% | 0% | $23,822,744 |
| Jefferies Financial Group Inc. | 1.2% | 568,084 | -12% | 0.21% | $22,569,977 |
| Sofinnova Investments, Inc. | 1.2% | 565,417 | +642% | 1.4% | $22,464,017 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 73,707 | $5,563,589 | -$4,596,205 | $75.48 | 3 |
| 2025 Q3 | 59,584,018 | $2,367,665,565 | +$56,490,678 | $39.73 | 172 |
| 2025 Q2 | 57,837,483 | $2,511,890,310 | -$147,323,035 | $43.43 | 180 |
| 2025 Q1 | 61,488,037 | $2,301,755,045 | +$131,273,428 | $37.36 | 165 |
| 2024 Q4 | 57,873,775 | $2,621,627,156 | +$63,332,211 | $45.30 | 156 |
| 2024 Q3 | 56,092,373 | $3,292,239,808 | +$134,061,710 | $58.74 | 139 |
| 2024 Q2 | 54,153,585 | $2,130,950,611 | -$9,265,142 | $39.35 | 137 |
| 2024 Q1 | 52,903,025 | $3,515,414,886 | +$773,333,688 | $66.45 | 138 |
| 2023 Q4 | 26,497 | $740,326 | +$740,326 | $27.94 | 2 |
| 2023 Q3 | 40,108,316 | $848,591,959 | +$848,589,611 | $21.30 | 72 |