| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| EVENTIDE ASSET MANAGEMENT, LLC | 11.32% | $57.4M | 4.86M | Eventide Asset Management, LLC | Jan 31, 2025 | |||
| Zone Healthcare Holdings, LLC | 9.9% | +25% | $85.7M | $17.6M | 4.31M | +25.9% | Dapice Joshua J. | Sep 30, 2025 |
| Farallon Capital Partners, L.P. | 9.7% | $77.1M | 4.2M | Dapice Joshua J. | Jun 30, 2025 | |||
| Wellington Hadley Harbor Aggregator IV, L.P. | 9% | +31.4% | $46.1M | $11.8M | 3.9M | +34.5% | Wellington Hadley Harbor Aggregator IV, L.P. | Mar 31, 2025 |
| WELLINGTON MANAGEMENT GROUP LLP | 9% | $46.1M | 3.9M | Wellington Management Group LLP | Mar 31, 2025 | |||
| Soleus BB SPV, LLC | 8.8% | $44.8M | 3.8M | Soleus Capital Management, L.P. | Mar 31, 2025 | |||
| MORGAN STANLEY | 8.6% | +25.7% | $74.3M | $16.1M | 3.74M | +27.7% | Morgan Stanley | Sep 30, 2025 |
| Sands Capital Life Sciences Pulse Fund II, L.P. | 8.2% | +12.9% | $65.4M | $7.62M | 3.57M | +13.2% | Sands Capital Life Sciences Pulse Fund II. L.P. | Jun 30, 2025 |
| RTW INVESTMENTS, LP | 7.6% | $39M | 3.3M | RTW Investments, LP | Mar 31, 2025 | |||
| BlackRock, Inc. | 6.4% | $55.2M | 2.78M | BlackRock, Inc. | Sep 30, 2025 | |||
| VANGUARD GROUP INC | 5.09% | $44M | 2.22M | The Vanguard Group | Sep 30, 2025 | |||
| PERCEPTIVE ADVISORS LLC | 3.68% | $23.8M | 1.59M | Perceptive Advisors LLC | Mar 31, 2025 | |||
| MILLENNIUM MANAGEMENT LLC | 1.8% | -70% | $15.8M | -$29.6M | 797K | -65.1% | Millennium Management LLC | Sep 30, 2025 |