| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| JENNISON ASSOCIATES LLC | 8.9% | +24% | $29,447,817 | +$5,797,046 | 12,584,537 | +25% | Jennison Associates LLC | 30 Sep 2025 |
| PRUDENTIAL FINANCIAL INC | 8.9% | +21% | $29,447,817 | +$5,132,486 | 12,584,537 | +21% | PRUDENTIAL FINANCIAL INC | 30 Sep 2025 |
| T. Rowe Price Investment Management, Inc. | 11% | +24% | $24,243,163 | +$4,674,939 | 10,360,326 | +24% | T. Rowe Price Investment Management, Inc. | 31 Oct 2025 |
| Bain Capital Life Sciences Opportunities III, LP | 10% | $15,676,942 | 9,677,125 | Bain Capital Life Sciences Opportunities III, LP | 30 Jun 2025 | |||
| Cormorant Asset Management, LP | 10% | +90% | $22,445,240 | +$10,745,240 | 9,591,983 | +92% | Cormorant Asset Management, LP | 30 Sep 2025 |
| Adage Capital Management, L.P. | 10% | $13,683,922 | 9,002,580 | Adage Capital Management, L.P. | 30 Jun 2025 | |||
| Alyeska Investment Group, L.P. | 6% | -39% | $13,572,000 | -$7,264,219 | 5,800,000 | -35% | Alyeska Investment Group, L.P. | 30 Sep 2025 |
| VANGUARD GROUP INC | 3.8% | $4,554,960 | 3,450,727 | The Vanguard Group | 30 Jun 2025 | |||
| CITADEL ADVISORS LLC | 3.4% | -36% | $7,371,644 | -$3,903,787 | 3,150,275 | -35% | Kenneth Griffin | 30 Sep 2025 |
| Nichtberger Steven | 3.3% | $4,005,539 | 3,034,499 | Nichtberger Steven | 30 Jun 2025 | |||
| BlackRock, Inc. | 1% | -86% | $1,180,934 | -$3,303,449 | 894,647 | -74% | BlackRock, Inc. | 30 Jun 2025 |
| Filer | Ownership | Holdings Value | Nb Shares | Share Change % |
|---|---|---|---|---|
| Bain Capital Life Sciences Investors, LLC | 10% | $22,644,473 | 9,677,125 | 0% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 9.2% | $20,661,634 | 8,829,758 | 0% |
| JENNISON ASSOCIATES LLC | 8.9% | $19,884,236 | 8,497,537 | +41% |
| T. Rowe Price Investment Management, Inc. | 8.7% | $19,569,000 | 8,362,489 | +23% |
| Cormorant Asset Management, LP | 5.2% | $11,700,000 | 5,000,000 | 0% |
| VANGUARD GROUP INC | 4.4% | $9,806,376 | 4,190,759 | +21% |
| Woodline Partners LP | 2.2% | $4,996,714 | 2,135,348 | +75% |
| HEIGHTS CAPITAL MANAGEMENT, INC | 2.2% | $4,877,033 | 2,084,202 | -34% |
| HEIGHTS CAPITAL MANAGEMENT, INC | 2.2% | $4,877,033 | 2,084,202 | -34% |
| BlackRock, Inc. | 1.7% | $3,792,840 | 1,620,872 | +67% |
| SUPERSTRING CAPITAL MANAGEMENT LP | 1.6% | $3,614,189 | 1,544,525 | +46% |
| MORGAN STANLEY | 1.5% | $3,450,742 | 1,474,676 | +11% |
| RENAISSANCE TECHNOLOGIES LLC | 1.4% | $3,134,250 | 1,339,423 | +962% |
| MARSHALL WACE, LLP | 1.4% | $3,102,942 | 1,326,043 | +594% |
| Alyeska Investment Group, L.P. | 1.4% | $3,042,000 | 1,300,000 | -73% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.3% | $3,031,000 | 1,294,949 | -41% |
| Schonfeld Strategic Advisors LLC | 1.1% | $2,443,353 | 1,044,169 | -30% |
| GEODE CAPITAL MANAGEMENT, LLC | 0.96% | $2,154,082 | 920,340 | +66% |
| Opaleye Management Inc. | 0.84% | $1,892,784 | 808,882 | |
| CITADEL ADVISORS LLC | 0.73% | $1,650,788 | 705,465 | -58% |
| Burkehill Global Management, LP | 0.73% | $1,638,000 | 700,000 | -63% |
| MILLENNIUM MANAGEMENT LLC | 0.72% | $1,607,142 | 686,813 | -20% |
| JPMORGAN CHASE & CO | 0.56% | $1,258,098 | 537,649 | +565% |
| TWO SIGMA INVESTMENTS, LP | 0.49% | $1,100,911 | 470,475 | +86% |
| UBS Group AG | 0.42% | $947,982 | 405,120 | -14% |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 71,298,009 | $166,850,266 | -$6,975,222 | $2.34 | 75 |
| 2025 Q2 | 72,777,604 | $110,698,611 | +$55,724,861 | $1.52 | 85 |
| 2025 Q1 | 36,304,416 | $50,331,238 | -$5,413,451 | $1.38 | 91 |
| 2024 Q4 | 38,433,072 | $87,225,765 | -$42,826,625 | $2.27 | 104 |
| 2024 Q3 | 48,049,164 | $226,749,029 | -$34,734,599 | $4.72 | 116 |
| 2024 Q2 | 50,803,155 | $380,009,358 | -$32,110,485 | $7.48 | 137 |
| 2024 Q1 | 51,050,461 | $870,920,794 | +$18,932,337 | $17.06 | 158 |
| 2023 Q4 | 13,929 | $316,188 | $22.70 | 1 | |
| 2023 Q3 | 40,903,206 | $622,567,029 | +$72,529,447 | $15.22 | 96 |
| 2023 Q2 | 36,439,842 | $470,446,385 | +$156,176,109 | $12.91 | 83 |
| 2023 Q1 | 24,550,692 | $203,032,448 | +$37,663,399 | $8.27 | 68 |
| 2022 Q4 | 19,877,471 | $183,864,776 | +$77,864,903 | $9.25 | 58 |
| 2022 Q3 | 11,480,868 | $7,459,359 | -$5,439,395 | $0.6491 | 41 |
| 2022 Q2 | 16,793,402 | $17,802,000 | -$3,028,529 | $1.06 | 46 |
| 2022 Q1 | 18,097,444 | $36,731,000 | -$1,708,091 | $2.03 | 51 |
| 2021 Q4 | 18,158,070 | $68,820,000 | -$10,112,110 | $3.79 | 58 |
| 2021 Q3 | 17,374,979 | $211,261,380 | +$20,908,305 | $12.16 | 58 |
| 2021 Q2 | 15,643,357 | $134,523,391 | -$5,543,238 | $8.60 | 58 |
| 2021 Q1 | 16,074,396 | $178,421,440 | +$381,267 | $11.10 | 64 |
| 2020 Q4 | 15,518,470 | $193,656,469 | -$3,199,162 | $12.48 | 53 |
| 2020 Q3 | 16,353,803 | $177,272,014 | -$992,123 | $10.84 | 53 |
| 2020 Q2 | 16,442,959 | $183,160,097 | +$5,139,607 | $11.14 | 51 |
| 2020 Q1 | 16,009,620 | $116,871,000 | -$3,057,825 | $7.30 | 41 |
| 2019 Q4 | 16,265,458 | $227,227,000 | +$175,618,187 | $13.97 | 40 |