CASTLE BIOSCIENCES INC - Common Stock (CSTL) Institutional Ownership

13F Institutional Holders and Ownership History from Q3 2019 to Q4 2025

Type / Class
Equity / Common Stock
Symbol
CSTL on Nasdaq
Shares outstanding
28,903,706
Price per share
$38.90
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
26,525,689
Total reported value
$603,808,452
% of total 13F portfolios
0%
Share change
-49,324
Value change
+$704,966
Number of holders
170
Price from insider filings
$38.90
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of CASTLE BIOSCIENCES INC - Common Stock (CSTL) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
BlackRock, Inc. 8.2% $47,017,281 2,338,005 BlackRock, Inc. 31 Mar 2025
VANGUARD GROUP INC 6.5% $36,852,279 1,832,535 The Vanguard Group 31 Dec 2024
Portolan Capital Management, LLC 5.6% $32,399,201 1,611,099 Portolan Capital Management, LLC 07 Apr 2025
DIMENSIONAL FUND ADVISORS LP 5.1% $33,563,827 1,474,089 Dimensional Fund Advisors LP 30 Sep 2025
WASATCH ADVISORS LP 3.5% $20,078,930 998,455 WASATCH ADVISORS LP 31 Mar 2025

As of 30 Sep 2025, 170 institutional investors reported holding 26,525,689 shares of CASTLE BIOSCIENCES INC - Common Stock (CSTL). This represents 92% of the company’s total 28,903,706 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of CASTLE BIOSCIENCES INC - Common Stock (CSTL) together control 73% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BlackRock, Inc. 11% 3,189,896 +1.1% 0% $72,633,931
VANGUARD GROUP INC 7.5% 2,172,318 +0.11% 0% $49,463,681
PRINCIPAL FINANCIAL GROUP INC 6.2% 1,794,355 -0.26% 0.02% $40,857,463
Portolan Capital Management, LLC 5.2% 1,515,111 +1.7% 1.9% $34,499,077
DIMENSIONAL FUND ADVISORS LP 5.1% 1,474,089 +7% 0.01% $33,564,113
Nuveen, LLC 3.3% 957,081 -11% 0.01% $21,792,735
BRAIDWELL LP 2.8% 822,735 0% 0.56% $18,733,676
STATE STREET CORP 2.5% 724,080 +2.3% 0% $16,487,302
AIGH Capital Management LLC 2.4% 707,287 5.6% $16,104,925
GEODE CAPITAL MANAGEMENT, LLC 2.4% 698,610 +1.3% 0% $15,909,607
WASATCH ADVISORS LP 2.3% 669,120 -36% 0.08% $15,235,862
Allianz Asset Management GmbH 2.2% 648,351 -9.2% 0.02% $14,762,953
PALISADE CAPITAL MANAGEMENT, LP 2.2% 638,656 +11% 0.4% $14,542,197
MILLENNIUM MANAGEMENT LLC 2% 575,089 +34% 0.01% $13,094,777
RENAISSANCE TECHNOLOGIES LLC 1.9% 562,600 -16% 0.02% $12,810,402
SCHRODER INVESTMENT MANAGEMENT GROUP 1.7% 494,950 -24% 0.01% $11,067,082
Parkman Healthcare Partners LLC 1.6% 475,568 +35% 1.2% $10,828,683
ACADIAN ASSET MANAGEMENT LLC 1.6% 451,652 -17% 0.02% $10,281,000
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 1.4% 400,000 0.3% $9,108,000
SILVERCREST ASSET MANAGEMENT GROUP LLC 1.3% 367,888 +31% 0.06% $8,376,810
GOLDMAN SACHS GROUP INC 1.2% 345,099 +26% 0% $7,857,904
Point72 Asset Management, L.P. 1.2% 336,958 0.02% $7,672,533
Connor, Clark & Lunn Investment Management Ltd. 1.2% 335,891 +166% 0.02% $7,648,238
BANK OF AMERICA CORP /DE/ 1.1% 315,370 -18% 0% $7,180,975
UBS Group AG 1% 291,362 -20% 0% $6,634,313

Institutional Holders of CASTLE BIOSCIENCES INC - Common Stock (CSTL) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 48,442 $1,884,302 +$225,974 $38.90 6
2025 Q3 26,525,689 $603,808,452 +$704,966 $22.77 170
2025 Q2 26,536,172 $541,804,431 +$16,368,992 $20.42 152
2025 Q1 25,785,418 $516,159,004 -$22,608,126 $20.02 180
2024 Q4 26,436,694 $704,576,091 +$9,096,275 $26.65 196
2024 Q3 25,751,192 $734,808,221 +$15,302,476 $28.52 187
2024 Q2 25,178,629 $548,104,565 +$5,427,151 $21.77 158
2024 Q1 24,910,305 $551,749,846 +$21,552,534 $22.15 148
2023 Q4 30,623 $660,844 +$142,924 $21.58 2
2023 Q3 23,077,637 $389,782,698 +$8,090,644 $16.89 133
2023 Q2 22,716,898 $311,677,195 -$4,364,825 $13.72 126
2023 Q1 22,064,743 $501,264,460 +$5,647,042 $22.72 147
2022 Q4 22,167,878 $521,815,946 +$5,459,327 $23.54 148
2022 Q3 20,819,895 $542,848,973 -$15,421,347 $26.08 146
2022 Q2 20,249,716 $444,356,707 -$121,088,812 $21.95 139
2022 Q1 22,730,722 $1,017,034,561 +$59,522,514 $44.86 151
2021 Q4 21,368,510 $914,802,811 -$58,371,992 $42.87 150
2021 Q3 21,467,953 $1,420,237,862 +$43,573,417 $66.50 184
2021 Q2 20,713,774 $1,514,902,972 +$1,506,061 $73.33 176
2021 Q1 21,293,307 $1,457,102,388 +$107,465,071 $68.46 172
2020 Q4 18,481,034 $1,241,807,552 +$365,467,827 $67.15 161
2020 Q3 13,395,783 $689,395,356 +$88,061,864 $51.45 144
2020 Q2 11,740,776 $443,028,646 +$168,799,403 $37.69 123
2020 Q1 7,140,225 $212,848,385 +$65,746,042 $29.81 86
2019 Q4 5,107,518 $175,544,000 +$15,966,469 $34.37 64
2019 Q3 4,867,946 $88,059,000 +$69,409,007 $18.09 55