CYTOKINETICS INC - COMMON STOCK (CYTK)

Historical Holders from Q1 2014 to Q4 2025

Symbol: CYTK on Nasdaq
Type / Class: Equity / COMMON STOCK
Shares outstanding: 119,358,581
All holders as of 30 Sep 2025: Q3 2025
Total 13F shares, excl. options: 140,918,559
Holdings value: $7,744,283,008
% of all portfolios: 0.01%
Number of holders: 376
Number of buys: 222
Number of sells: 127
Average buys %: +0.01%
Average sells %: -0%

Reported Shares, Excluding Options vs Price

Reported Value, Excluding Options

Total Investors

Significant Owners of CYTOKINETICS INC - COMMON STOCK (CYTK) based on Schedule 13D/G filings

Filer	Ownership	Change %	Holdings Value	Net Change	Nb Shares	Change %	Reporting Name	Report Period
T. Rowe Price Investment Management, Inc.	16%	+8.7%	$1,049,591,620	+$82,161,518	19,097,373	+8.5%	T. Rowe Price Investment Management, Inc.	30 Sep 2025
FMR LLC	11%	+17%	$401,039,860	+$59,831,622	13,101,596	+18%	FMR LLC	31 Jul 2025
VANGUARD GROUP INC	10%		$444,698,440		11,915,821		The Vanguard Group	31 Dec 2024
STATE STREET CORP	4.7%		$308,728,677		5,617,334		STATE STREET CORPORATION	30 Sep 2025

As of 30 Sep 2025 CYTOKINETICS INC - COMMON STOCK (CYTK) has 376 institutional shareholders that have filed 13F forms with the Securities Exchange Commission (SEC). These institutions hold a total of 140,918,559 shares of the company stock as of 30 Sep 2025.

Institutional Holders of CYTOKINETICS INC - COMMON STOCK (CYTK) across Reporting Periods

Period	Reported Shares, Excl. Options	Value, Excl. Options	Value Change	Puts Notional Value	Calls Notional Value	Price	Investors
2025 Q4	2,493	$158,405	+$43,461			$63.54	2
2025 Q3	140,918,559	$7,744,283,008	+$248,284,834	$63,649,799	$286,087,755	$54.96	376
2025 Q2	137,673,271	$4,548,796,640	+$22,761,499	$36,728,648	$118,296,052	$33.04	309
2025 Q1	134,841,154	$5,424,120,165	+$124,947,280	$35,302,435	$144,888,035	$40.19	351
2024 Q4	131,307,506	$6,182,587,231	-$258,868,970	$85,101,547	$150,216,019	$47.04	342
2024 Q3	134,972,901	$7,127,084,491	-$76,106,017	$124,504,036	$230,315,666	$52.80	348
2024 Q2	135,460,541	$7,337,313,472	+$958,985,342	$107,822,841	$164,771,816	$54.18	351
2024 Q1	116,704,973	$8,183,106,182	+$219,853,893	$373,427,191	$412,192,063	$70.11	392
2023 Q4	332,271	$27,731,943	+$4,934,911			$83.49	4
2023 Q3	108,419,837	$3,194,217,873	+$11,036,096	$42,846,624	$20,141,414	$29.46	244
2023 Q2	106,646,104	$3,480,589,719	-$38,310,785	$9,365,202	$6,027,128	$32.62	246
2023 Q1	107,552,318	$3,783,669,618	+$68,564,865	$6,721,290	$6,695,138	$35.19	255
2022 Q4	106,314,317	$4,879,277,216	+$70,020,188	$10,059,490	$18,409,490	$45.82	269
2022 Q3	89,735,826	$4,346,616,824	-$100,372,482	$6,565,000	$20,012,000	$48.45	262
2022 Q2	91,896,852	$3,607,650,636	+$406,560,690	$4,949,000	$13,543,134	$39.29	249
2022 Q1	81,782,994	$3,010,372,611	+$152,134,040	$5,060,000	$11,255,000	$36.81	225
2021 Q4	90,115,859	$4,104,593,563	+$33,336,758	$5,223,000	$8,222,000	$45.58	238
2021 Q3	89,182,505	$3,184,083,008	+$487,903,084	$5,149,000	$15,568,000	$35.74	201
2021 Q2	75,500,552	$1,494,253,848	+$7,758,286	$5,314,000	$9,942,000	$19.79	181
2021 Q1	74,703,392	$1,736,582,618	+$70,863,620	$2,907,000	$5,527,000	$23.26	186
2020 Q4	72,427,397	$1,504,711,565	-$7,199,858	$4,081,000	$10,876,800	$20.78	173
2020 Q3	68,793,341	$1,486,919,340	+$223,898,251	$37,775,000	$52,671,000	$21.65	176
2020 Q2	57,898,590	$1,364,648,639	+$106,425,753	$5,996,000	$3,552,000	$23.57	154
2020 Q1	52,639,764	$620,477,415	-$6,055,336	$8,644,000	$8,135,000	$11.79	137
2019 Q4	54,325,360	$576,376,840	+$110,957,221	$2,648,000	$1,524,000	$10.61	135
2019 Q3	42,728,625	$486,251,307	+$8,024,890	$335,000	$3,707,000	$11.38	137
2019 Q2	42,086,538	$473,445,943	+$63,742,611	$734,000	$6,837,000	$11.25	126
2019 Q1	39,043,049	$315,931,137	+$3,212,559	$372,000	$489,000	$8.09	122
2018 Q4	39,532,757	$249,816,749	+$227,833	$370,000	$194,000	$6.32	119
2018 Q3	38,246,560	$376,723,063	+$11,812,411	$0	$684,000	$9.85	110
2018 Q2	37,494,054	$311,218,002	+$5,853,383	$120,000	$545,000	$8.30	119
2018 Q1	36,846,465	$265,286,731	-$12,318,500	$481,000	$746,000	$7.20	118
2017 Q4	38,426,331	$313,265,401	-$31,639,128	$1,356,000	$849,000	$8.15	124
2017 Q3	38,980,718	$565,174,810	+$21,918,351	$3,519,000	$4,082,000	$14.50	125
2017 Q2	38,117,536	$461,334,423	+$119,363,256	$1,746,000	$1,022,000	$12.10	133
2017 Q1	28,035,384	$360,246,466	+$62,643,666	$308,000	$1,101,000	$12.85	102
2016 Q4	26,418,852	$320,904,146	-$2,121,679	$123,000	$167,000	$12.15	97
2016 Q3	26,660,001	$244,742,898	+$491,496	$340,000	$1,918,000	$9.18	87
2016 Q2	26,539,739	$251,856,889	+$5,256,368	$302,000	$784,000	$9.49	92
2016 Q1	26,619,209	$187,496,987	-$3,874,309	$515,000	$1,277,000	$7.05	103
2015 Q4	26,471,070	$276,904,125	+$55,278,305	$1,384,000	$1,535,000	$10.46	124
2015 Q3	21,585,065	$144,503,660	+$6,050,338	$88,000	$1,821,000	$6.69	102
2015 Q2	20,416,358	$137,192,627	+$7,722,814	$853,000	$1,973,000	$6.72	93
2015 Q1	19,594,890	$132,978,626	+$965,004	$740,000	$1,117,000	$6.78	91
2014 Q4	19,143,626	$153,243,250	+$252,136	$1,170,000	$1,660,000	$8.01	83
2014 Q3	19,775,788	$69,615,049	-$7,582,600	$228,000	$419,000	$3.52	80
2014 Q2	20,755,367	$99,208,515	-$24,735,703	$1,537,000	$2,300,000	$4.78	84
2014 Q1	22,477,555	$213,589,026	+$39,996,206	$13,994,000	$17,860,000	$9.50	103