| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| JPMORGAN CHASE & CO | 10.8% | +36.3% | $2.98B | $1.02B | 23M | +51.8% | JPMORGAN CHASE & CO. | Aug 29, 2025 |
| Darwin Global Management, Ltd. | 9.7% | +13.3% | $2.95B | $729M | 20.5M | +32.9% | Darwin Global Management, Ltd. | Sep 30, 2025 |
| VANGUARD GROUP INC | 10.18% | $1.25B | 18.2M | The Vanguard Group | Dec 31, 2024 | |||
| BlackRock, Inc. | 5.1% | $639M | 9.73M | BlackRock, Inc. | Jun 30, 2025 | |||
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.3% | -43.3% | $998M | -$619M | 6.93M | -38.3% | T. Rowe Price Associates, Inc. | Sep 30, 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 211M | $30.3B | +$449M | $144.01 | 546 |
| 2025 Q2 | 210M | $21.1B | +$1.36B | $100.64 | 511 |
| 2025 Q1 | 198M | $15.1B | +$439M | $76.29 | 434 |
| 2024 Q4 | 193M | $13.3B | +$360M | $69.04 | 433 |
| 2024 Q3 | 186M | $13.6B | +$788M | $73.00 | 417 |
| 2024 Q2 | 175M | $11.7B | +$1.88B | $67.00 | 386 |
| 2024 Q1 | 148M | $4.02B | -$32M | $27.13 | 292 |
| 2023 Q4 | 761K | $23.6M | -$1.87M | $30.99 | 4 |
| 2023 Q3 | 146M | $3.69B | +$65.8M | $25.25 | 245 |
| 2023 Q2 | 145M | $3.06B | +$10.5M | $21.10 | 217 |
| 2023 Q1 | 145M | $2.47B | +$36.8M | $17.05 | 225 |
| 2022 Q4 | 143M | $2.86B | +$305M | $19.98 | 220 |
| 2022 Q3 | 122M | $2.63B | -$229M | $21.54 | 222 |
| 2022 Q2 | 125M | $2.46B | +$53M | $19.72 | 192 |
| 2022 Q1 | 125M | $2.93B | +$71.2M | $23.50 | 203 |
| 2021 Q4 | 123M | $3.34B | -$21.8M | $27.24 | 197 |
| 2021 Q3 | 123M | $3.39B | +$40M | $27.54 | 184 |
| 2021 Q2 | 121M | $3.45B | +$433M | $28.46 | 192 |
| 2021 Q1 | 106M | $3.62B | -$7.46M | $34.06 | 191 |
| 2020 Q4 | 107M | $3.58B | -$45.4M | $33.29 | 199 |
| 2020 Q3 | 109M | $3.49B | -$56.3M | $32.14 | 192 |
| 2020 Q2 | 111M | $3.04B | +$367M | $27.54 | 179 |
| 2020 Q1 | 96.9M | $1.55B | -$33.1M | $16.03 | 154 |
| 2019 Q4 | 98.3M | $2.35B | -$38.9M | $23.88 | 168 |
| 2019 Q3 | 98.3M | $1.73B | -$529M | $17.64 | 149 |
| 2019 Q2 | 126M | $3.23B | +$1.16B | $25.60 | 161 |
| 2019 Q1 | 82.1M | $2.39B | -$5.04M | $29.07 | 147 |
| 2018 Q4 | 82.3M | $1.08B | -$9.3M | $13.12 | 118 |
| 2018 Q3 | 80.9M | $1.64B | -$43.3M | $20.22 | 119 |
| 2018 Q2 | 82.4M | $1.95B | +$34.2M | $23.65 | 123 |
| 2018 Q1 | 81.8M | $1.84B | +$128M | $22.52 | 124 |
| 2017 Q4 | 75.9M | $2.37B | +$46.2M | $31.18 | 123 |
| 2017 Q3 | 73.7M | $2.29B | +$541M | $31.21 | 139 |
| 2017 Q2 | 55.5M | $952M | +$47.9M | $17.16 | 106 |
| 2017 Q1 | 56.9M | $996M | +$70.3M | $17.51 | 94 |
| 2016 Q4 | 57.8M | $765M | +$2.35M | $13.23 | 95 |
| 2016 Q3 | 57.5M | $834M | +$19.2M | $14.52 | 93 |
| 2016 Q2 | 56.5M | $557M | -$8.09M | $9.86 | 103 |
| 2016 Q1 | 57M | $722M | -$12.9M | $12.67 | 95 |
| 2015 Q4 | 56.6M | $1.03B | +$272K | $18.15 | 109 |
| 2015 Q3 | 56.8M | $1.05B | +$35.4M | $18.57 | 117 |
| 2015 Q2 | 53.5M | $1.31B | +$18.2M | $24.42 | 113 |
| 2015 Q1 | 51.6M | $1.07B | +$253M | $20.80 | 114 |
| 2014 Q4 | 41.6M | $644M | +$12.7M | $15.47 | 91 |
| 2014 Q3 | 41.3M | $539M | +$116M | $13.05 | 99 |
| 2014 Q2 | 29.7M | $593M | -$7.58K | $19.98 | 101 |
| 2014 Q1 | 29.2M | $555M | +$49.2M | $19.04 | 106 |