| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Invus Global Management, LLC | 10.6% | +35% | $52M | $26M | 14.8M | +100% | Invus Public Equities, L.P. | Jun 30, 2025 |
| Samsara BioCapital, L.P. | 7.4% | +25% | $56.2M | $22.3M | 13.5M | +65.9% | Srinivas Akkaraju | Nov 17, 2025 |
| Andera Partners | 8.8% | +32.9% | $78.1M | $39M | 12.3M | +100% | Andera Partners | Jun 30, 2025 |
| BIOTECHNOLOGY VALUE FUND L P | 4.99% | -18.5% | $39.7M | $4.25M | 9.57M | +12% | BVF PARTNERS L P/IL | Nov 17, 2025 |
| New Enterprise Associates 17, L.P. | 6% | $26.3M | 8.35M | New Enterprise Associates 17, L.P. | May 7, 2025 | |||
| Sofinnova Crossover I | 7.2% | $24.5M | 7.79M | Sofinnova Crossover I SLP | Dec 31, 2024 | |||
| Yiheng Capital Management, L.P. | 5.46% | -35.6% | $41.9M | $18M | 7.6M | +75.4% | Yiheng Capital Partners, L.P. | Sep 30, 2025 |
| PERCEPTIVE ADVISORS LLC | 4.99% | -13.5% | $40.3M | $9.63M | 7.3M | +31.4% | Perceptive Advisors LLC | Sep 30, 2025 |
| Broqua Pierre | 4.3% | $12.9M | 4.1M | Pierre Broqua | Dec 31, 2024 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 5.11M | $29.4M | +$1.09M | $5.79 | 15 |
| 2025 Q2 | 4.93M | $15.7M | +$215K | $3.19 | 12 |
| 2025 Q1 | 4.86M | $12.2M | -$1.72M | $2.94 | 8 |
| 2024 Q4 | 5.45M | $11.7M | +$1.28M | $2.14 | 7 |
| 2024 Q3 | 4.85M | $9.06M | -$1.41K | $1.87 | 7 |
| 2024 Q2 | 4.85M | $14.5M | -$19.4K | $2.99 | 7 |
| 2024 Q1 | 4.85M | $17.6M | -$5.02K | $3.62 | 8 |
| 2023 Q4 | 11.9K | $44K | -$4.88K | $3.70 | 1 |
| 2023 Q3 | 4.86M | $20.6M | +$102K | $4.20 | 7 |
| 2023 Q2 | 4.83M | $19.5M | -$1.02M | $4.04 | 8 |
| 2023 Q1 | 5.13M | $18.3M | +$1.09M | $3.64 | 8 |
| 2022 Q4 | 4.81M | $21.9M | -$19.7M | $4.46 | 5 |
| 2022 Q3 | 8.93M | $33.1M | -$1M | $3.86 | 7 |
| 2022 Q2 | 9.11M | $51.8M | +$29.3M | $5.71 | 9 |
| 2022 Q1 | 3.93M | $45M | +$2.06M | $11.40 | 9 |
| 2021 Q4 | 3.76M | $51.3M | +$608K | $13.66 | 8 |
| 2021 Q3 | 3.71M | $52.5M | +$30.4M | $14.15 | 12 |
| 2021 Q2 | 1.56M | $21.3M | -$848K | $13.58 | 14 |
| 2021 Q1 | 1.62M | $23.8M | -$15.6M | $14.69 | 13 |
| 2020 Q4 | 2.73M | $39.2M | -$22.1M | $14.50 | 15 |
| 2020 Q3 | 4.02M | $47.5M | +$47.5M | $11.81 | 17 |