| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| ARCH Venture Fund IX, L.P. | 13% | $44,807,329 | 2,759,072 | ARCH Venture Fund IX, L.P. | 30 Sep 2025 | |||
| Innovative Cellular Therapeutics Holdings Ltd | 9.8% | $30,856,000 | 1,900,000 | Innovative Cellular Therapeutics Holdings Ltd | 06 Nov 2025 | |||
| Foresite Capital Fund IV, L.P. | 7.6% | $23,622,964 | 1,454,616 | James B. Tananbaum | 30 Sep 2025 | |||
| Gates Frontier, LLC | 5.6% | 1,040,964 | Gates Frontier, LLC | 25 Jul 2025 | ||||
| NEWTON (PTC) Ltd | 3.9% | $12,256,296 | 754,698 | Newton (PTC) Limited | 30 Sep 2025 |
As of 30 Sep 2025, 57 institutional investors reported holding 9,636,348 shares of Lyell Immunopharma, Inc. - Common Stock, par value $0.0001 (LYEL). This represents 50% of the company’s total 19,139,684 outstanding shares.
The largest institutional shareholders of Lyell Immunopharma, Inc. - Common Stock, par value $0.0001 (LYEL) together control 49% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| ARCH Venture Management, LLC | 14% | 2,759,072 | +52% | 9.1% | $44,807,329 |
| MWG Management Ltd. | 5.3% | 1,008,116 | 20% | $16,371,804 | |
| Foresite Capital Management IV, LLC | 4.2% | 800,399 | 0% | 7.1% | $12,998,480 |
| VANGUARD GROUP INC | 4.1% | 779,004 | +76% | 0% | $12,651,024 |
| Orland Properties Ltd | 3.9% | 754,698 | 2.6% | $12,256,296 | |
| Almitas Capital LLC | 3% | 577,807 | -0.38% | 2.1% | $9,383,586 |
| Foresite Capital Management V, LLC | 2.5% | 477,078 | +17% | 7.1% | $7,747,747 |
| venBio Partners LLC | 2.5% | 473,479 | 0% | 4.4% | $7,689,299 |
| CITADEL ADVISORS LLC | 1.8% | 339,491 | +25% | 0% | $5,513,334 |
| Alphabet Inc. | 1.5% | 293,256 | 0% | 0.2% | $4,762,477 |
| BlackRock, Inc. | 0.92% | 176,806 | +22% | 0% | $2,871,329 |
| HSG Holding Ltd | 0.8% | 152,299 | 0% | 0% | $73,104 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.68% | 130,257 | +26% | 0% | $2,116,079 |
| MILLENNIUM MANAGEMENT LLC | 0.65% | 125,361 | +140% | 0% | $2,035,863 |
| RBF Capital, LLC | 0.5% | 95,631 | -4.4% | 0.07% | $1,553,047 |
| MIC Capital Management UK LLP | 0.45% | 87,028 | 0% | 0.28% | $1,413,335 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.42% | 79,510 | +29% | 0% | $1,291,242 |
| RENAISSANCE TECHNOLOGIES LLC | 0.33% | 63,990 | -4.8% | 0% | $1,039,198 |
| ORBIMED ADVISORS LLC | 0.27% | 51,727 | 0% | 0.02% | $840,046 |
| Ikarian Capital, LLC | 0.23% | 43,799 | 0% | 0.16% | $711,296 |
| JOHNSON & JOHNSON | 0.22% | 41,165 | 0.13% | $668,520 | |
| MORGAN STANLEY | 0.19% | 37,020 | +44% | 0% | $601,204 |
| STATE STREET CORP | 0.18% | 33,752 | -0.28% | 0% | $548,132 |
| CANADA PENSION PLAN INVESTMENT BOARD | 0.15% | 29,411 | 0% | 0% | $477,635 |
| NORTHERN TRUST CORP | 0.15% | 28,128 | +51% | 0% | $456,798 |