| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Frazier Life Sciences Public Fund, L.P. | 12% | -14% | $72,562,680 | +$9,264,602 | 5,224,095 | +15% | Patrick J. Heron | 26 Sep 2025 |
| WELLINGTON MANAGEMENT GROUP LLP | 11% | +57% | $84,412,721 | +$44,744,691 | 4,823,336 | +113% | Wellington Management Group LLP | 30 Sep 2025 |
| ORBIMED ADVISORS LLC | 9% | $55,600,100 | 4,002,887 | ORBIMED ADVISORS LLC | 26 Sep 2025 | |||
| New Enterprise Associates 17, L.P. | 8.1% | $63,340,795 | 3,619,474 | Edward T. Mathers | 06 Nov 2025 | |||
| Deep Track Capital, LP | 6.6% | $30,399,543 | 2,188,592 | Deep Track Capital, LP | 30 Jun 2025 | |||
| Norwest Venture Partners XVI, LP | 4.8% | $29,738,337 | 2,140,989 | Tiba Aynechi | 26 Sep 2025 | |||
| Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | 4.5% | $35,304,395 | 2,017,394 | Wellington Biomedical Innovation Master Investors (Cayman) II, L.P. | 30 Sep 2025 | |||
| Hawryluk P. Kent | 4.3% | $34,925,782 | 1,995,759 | P. Kent Hawryluk | 30 Sep 2025 |
As of 30 Sep 2025, 117 institutional investors reported holding 47,790,065 shares of MBX Biosciences, Inc. - Common Stock, par value $0.0001 per share (MBX). This represents 103% of the company’s total 46,413,000 outstanding shares.
The largest institutional shareholders of MBX Biosciences, Inc. - Common Stock, par value $0.0001 per share (MBX) together control 94% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 14% | 6,652,013 | +11% | 3.5% | $116,410,228 |
| WELLINGTON MANAGEMENT GROUP LLP | 10% | 4,823,336 | +113% | 0.01% | $84,408,382 |
| ORBIMED ADVISORS LLC | 8.6% | 4,002,887 | 0% | 1.7% | $70,050,523 |
| NEA Management Company, LLC | 7.8% | 3,614,486 | 0% | 3.5% | $63,253,505 |
| Deep Track Capital, LP | 6.8% | 3,150,000 | +44% | 1.5% | $55,125,000 |
| NVP ASSOCIATES, LLC | 4.6% | 2,136,335 | 0% | 23% | $37,385,863 |
| EcoR1 Capital, LLC | 4.6% | 2,123,604 | +85% | 1.8% | $37,163,070 |
| Kynam Capital Management, LP | 4.3% | 2,000,000 | 2.6% | $35,000,000 | |
| BlackRock, Inc. | 4.2% | 1,957,461 | +94% | 0% | $34,255,569 |
| VANGUARD GROUP INC | 3.6% | 1,677,362 | +61% | 0% | $29,353,836 |
| Driehaus Capital Management LLC | 3.3% | 1,539,639 | -2.1% | 0.19% | $26,943,683 |
| FRANKLIN RESOURCES INC | 2.8% | 1,307,288 | +164% | 0.01% | $22,877,540 |
| Cormorant Asset Management, LP | 2.6% | 1,225,000 | +75% | 1.5% | $21,437,500 |
| Woodline Partners LP | 2.6% | 1,201,150 | +33% | 0.1% | $21,020,125 |
| CITADEL ADVISORS LLC | 2.1% | 996,083 | 0.01% | $17,431,453 | |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.1% | 954,726 | -29% | 0% | $16,709,000 |
| Parkman Healthcare Partners LLC | 1.7% | 773,304 | -11% | 1.5% | $13,532,820 |
| MILLENNIUM MANAGEMENT LLC | 1.4% | 655,416 | -15% | 0.01% | $11,469,780 |
| TCG Crossover Management, LLC | 1.4% | 650,000 | 0% | 0.56% | $11,375,000 |
| Point72 Asset Management, L.P. | 1.4% | 627,667 | -36% | 0.02% | $10,984,173 |
| GEODE CAPITAL MANAGEMENT, LLC | 1% | 473,932 | +36% | 0% | $8,295,948 |
| GOLDMAN SACHS GROUP INC | 0.77% | 358,121 | 0% | $6,267,118 | |
| STATE STREET CORP | 0.69% | 319,274 | +20% | 0% | $5,587,295 |
| Schonfeld Strategic Advisors LLC | 0.61% | 282,677 | -55% | 0.03% | $4,946,847 |
| Rock Springs Capital Management LP | 0.61% | 282,624 | 0.29% | $4,945,920 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 5,066 | $159,494 | +$150,064 | $31.54 | 3 |
| 2025 Q3 | 47,790,065 | $836,364,494 | +$203,956,800 | $17.50 | 117 |
| 2025 Q2 | 36,839,365 | $420,338,016 | +$15,668,027 | $11.41 | 87 |
| 2025 Q1 | 35,666,401 | $263,220,263 | +$14,436,866 | $7.38 | 79 |
| 2024 Q4 | 32,941,714 | $606,485,118 | +$46,248,268 | $18.43 | 63 |
| 2024 Q3 | 30,280,441 | $783,422,213 | +$783,375,221 | $25.98 | 44 |