Milestone Pharmaceuticals Inc. - Common Stock (MIST)

Historical Holders from Q2 2019 to Q4 2025

Type / Class
Equity / Common Stock
Symbol
MIST on Nasdaq
Shares outstanding
89,506,929
Price per share
$2.02
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares as of 30 Sep 2025
34,138,461
Holdings value
$68,276,752
% of all portfolios
0%
Share change
+22,320,755
Value change
+$44,826,869
Average buys %
+0%
Average sells %
-0%
Number of holders
61
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Milestone Pharmaceuticals Inc. - Common Stock (MIST) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
RTW INVESTMENTS, LP 9.9% -0.9% $18,310,336 +$7,029,150 9,155,168 +62% RTW Investments, LP 30 Sep 2025
Trails Edge Capital Partners, LP 9.9% 0% $18,035,760 +$339,996 9,017,880 +1.9% Trails Edge Capital Partners, LP 30 Sep 2025
Propel Bio Management, LLC 9.9% $21,001,011 8,861,186 Propel Bio Management, LLC 11 Jul 2025
Adage Capital Management, L.P. 10% $17,318,128 8,659,064 Adage Capital Management, L.P. 30 Sep 2025
INTEGRATED CORE STRATEGIES (US) LLC 0.6% $248,003 322,082 Integrated Core Strategies (US) LLC 31 Mar 2025
As of 30 Sep 2025, Milestone Pharmaceuticals Inc. - Common Stock (MIST) has 61 institutional shareholders filing 13F forms. They hold 34,138,461 shares of 89,506,929 outstanding shares (38%) .

Top 25 institutional shareholders own 37% of the company.

Filer Ownership Nb Shares Share Change % Portfolio % Holdings Value
ADAGE CAPITAL PARTNERS GP, L.L.C. 7.8% 6,976,000 0.02% $13,952,000
Propel Bio Management, LLC 5.7% 5,124,890 +186% 10% $10,249,780
ORBIMED ADVISORS LLC 3.6% 3,221,828 0.15% $6,443,656
MORGAN STANLEY 3.3% 2,969,067 +262% 0% $5,938,134
Simplify Asset Management Inc. 3.2% 2,832,974 +186% 0.11% $5,665,948
RTW INVESTMENTS, LP 2.8% 2,506,102 0% 0.06% $5,012,204
Pathstone Holdings, LLC 1.1% 1,000,000 0.01% $2,000,000
SPHERA FUNDS MANAGEMENT LTD. 0.92% 820,000 0.39% $1,640,000
TORONTO DOMINION BANK 0.84% 750,000 0% 0% $1,500,000
Affinity Asset Advisors, LLC 0.74% 666,666 0.12% $1,333,332
Boxer Capital Management, LLC 0.74% 666,666 0.42% $1,333,332
TWO SIGMA INVESTMENTS, LP 0.74% 666,551 0% $1,333,102
Lion Point Capital, LP 0.74% 658,553 +20% 7.5% $1,317,106
CITADEL ADVISORS LLC 0.57% 512,067 0% $1,024,134
MARSHALL WACE, LLP 0.47% 425,028 0% $850,056
JANE STREET GROUP, LLC 0.46% 408,492 +1179% 0% $816,984
MILLENNIUM MANAGEMENT LLC 0.45% 401,559 0% $803,118
UBS Group AG 0.44% 397,534 +23% 0% $795,068
GOLDMAN SACHS GROUP INC 0.4% 356,567 +199% 0% $713,134
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.29% 256,772 +305% 0% $513,544
TWO SIGMA ADVISERS, LP 0.26% 234,041 0% $468,082
AMH Equity Ltd 0.26% 231,671 0.58% $463,342
Quadrature Capital Ltd 0.25% 223,470 0.01% $448,057
Aptus Capital Advisors, LLC 0.23% 210,200 0% $420,400
GUARDIAN WEALTH ADVISORS, LLC / NC 0.23% 210,200 0.03% $420,400

Institutional Holders of Milestone Pharmaceuticals Inc. - Common Stock (MIST) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price Investors
2025 Q4 28,861 $58,299 +$24,583 $2.02 1
2025 Q3 34,138,461 $68,276,752 +$44,826,869 $2.00 61
2025 Q2 11,817,806 $22,925,663 +$893,026 $1.94 43
2025 Q1 11,824,370 $9,461,152 -$26,033,744 $0.8001 43
2024 Q4 24,546,580 $57,928,983 -$9,794,955 $2.36 46
2024 Q3 28,677,385 $43,589,418 -$2,288,269 $1.52 41
2024 Q2 30,178,631 $39,890,373 -$1,767,213 $1.32 40
2024 Q1 31,068,273 $55,610,121 +$23,678,681 $1.79 40
2023 Q4 20,000 $33,400 -$312,751 $1.67 1
2023 Q3 19,354,422 $59,997,697 -$3,310,726 $3.10 37
2023 Q2 20,469,589 $58,338,295 -$3,166,998 $2.85 46
2023 Q1 21,502,003 $84,717,660 -$10,244,768 $3.94 47
2022 Q4 23,665,827 $93,721,126 -$29,515,026 $3.96 53
2022 Q3 20,387,785 $187,355,531 +$9,681,072 $9.19 42
2022 Q2 20,815,190 $127,101,065 -$2,809,701 $6.14 28
2022 Q1 20,219,084 $129,802,503 +$5,072,385 $6.42 26
2021 Q4 19,407,262 $127,117,931 +$2,000,583 $6.55 25
2021 Q3 19,945,609 $113,888,639 -$1,092,679 $5.71 29
2021 Q2 20,138,543 $110,762,000 -$854,689 $5.50 30
2021 Q1 20,274,519 $117,387,000 -$1,994,223 $5.79 31
2020 Q4 20,560,309 $137,755,000 +$33,982,379 $6.70 32
2020 Q3 15,470,627 $113,249,000 +$42,783,135 $7.32 28
2020 Q2 9,741,517 $36,822,000 +$2,941,708 $3.78 22
2020 Q1 9,230,018 $16,982,000 -$32,674,933 $1.84 15
2019 Q4 14,376,929 $230,174,000 +$20,228,919 $16.01 23
2019 Q3 13,069,429 $239,621,000 -$2,841,712 $18.65 22
2019 Q2 13,080,782 $350,494,000 +$350,494,352 $27.15 23