| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BIOTECHNOLOGY VALUE FUND L P | 9.2% | +28.6% | $23.9M | $5.35M | 5.66M | +28.8% | BVF PARTNERS L P/IL | Mar 31, 2025 |
| Dimension Capital I, L.P. | 7.7% | $23M | 4.76M | Adam Goulburn | May 16, 2024 | |||
| BlackRock, Inc. | 6.3% | $16.2M | 3.84M | BlackRock, Inc. | Dec 31, 2024 | |||
| Avoro Capital Advisors LLC | 6.1% | -14.3% | $18M | -$2.99M | 3.73M | -14.3% | Avoro Capital Advisors LLC | Jun 30, 2025 |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 5.5% | $14.2M | 3.36M | SUVRETTA CAPITAL MANAGEMENT, LLC | Apr 9, 2025 | |||
| VANGUARD GROUP INC | 5.13% | $13.3M | 3.16M | The Vanguard Group | Dec 31, 2024 | |||
| FMR LLC | 2.8% | $7.07M | 1.75M | FMR LLC | May 30, 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 0 | $0 | -$361 | 0 | |
| 2025 Q2 | 62.2M | $281M | +$12M | $4.51 | 115 |
| 2025 Q1 | 59.5M | $276M | -$11.9M | $4.64 | 105 |
| 2024 Q4 | 61M | $423M | +$79.1M | $6.94 | 104 |
| 2024 Q3 | 49.8M | $264M | +$18.2M | $5.30 | 81 |
| 2024 Q2 | 45.8M | $171M | +$22M | $3.74 | 74 |
| 2024 Q1 | 39.9M | $281M | -$271K | $7.05 | 67 |
| 2023 Q4 | 12.5K | $70.4K | -$454K | $5.65 | 1 |
| 2023 Q3 | 42M | $201M | +$10.9M | $4.79 | 72 |
| 2023 Q2 | 39.7M | $272M | -$3.2M | $6.85 | 68 |
| 2023 Q1 | 39.8M | $310M | -$11.1M | $7.79 | 69 |
| 2022 Q4 | 41.2M | $314M | +$7.27M | $7.61 | 65 |
| 2022 Q3 | 40.2M | $328M | -$4.08M | $8.17 | 67 |
| 2022 Q2 | 38.8M | $375M | -$12M | $9.67 | 53 |
| 2022 Q1 | 39.9M | $560M | +$42M | $14.02 | 52 |
| 2021 Q4 | 36.3M | $742M | +$28.4M | $20.42 | 53 |
| 2021 Q3 | 34.9M | $759M | +$62.1M | $22.28 | 55 |
| 2021 Q2 | 32.1M | $705M | +$705M | $22.70 | 48 |