| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Flynn James E | 28% | $1,563,269,209 | 23,582,278 | Deerfield Management Company, L.P. | 31 Dec 2024 | |||
| VANGUARD GROUP INC | 6.8% | $298,295,985 | 4,499,864 | The Vanguard Group | 31 Dec 2024 | |||
| BlackRock, Inc. | 5% | +10% | $222,762,334 | +$26,073,375 | 3,338,764 | +13% | BlackRock, Inc. | 30 Jun 2025 |
As of 30 Sep 2025, 194 institutional investors reported holding 72,412,845 shares of Nuvalent, Inc. - Class A Stock (NUVL). This represents 108% of the company’s total 66,775,280 outstanding shares.
The largest institutional shareholders of Nuvalent, Inc. - Class A Stock (NUVL) together control 98% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. | 27% | 17,991,024 | 0% | 24% | $1,555,863,756 |
| FMR LLC | 15% | 10,013,237 | +0.45% | 0.05% | $865,944,758 |
| Paradigm Biocapital Advisors LP | 7.9% | 5,269,433 | 0% | 13% | $455,700,566 |
| VANGUARD GROUP INC | 6.9% | 4,605,007 | +1.8% | 0.01% | $398,241,005 |
| BlackRock, Inc. | 6.1% | 4,085,795 | +0.98% | 0.01% | $353,339,552 |
| WELLINGTON MANAGEMENT GROUP LLP | 3.4% | 2,300,865 | +46% | 0.03% | $198,978,805 |
| JANUS HENDERSON GROUP PLC | 3.3% | 2,188,674 | +23% | 0.09% | $189,340,492 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.7% | 1,810,420 | +0.84% | 0.02% | $156,566,000 |
| JPMORGAN CHASE & CO | 2.5% | 1,674,009 | +40% | 0.01% | $144,768,373 |
| STATE STREET CORP | 2.4% | 1,574,747 | +5.7% | 0% | $136,184,121 |
| PERCEPTIVE ADVISORS LLC | 2.3% | 1,562,336 | +14% | 4% | $135,110,817 |
| Commodore Capital LP | 2.1% | 1,400,000 | +1.8% | 5.9% | $121,072,000 |
| RA CAPITAL MANAGEMENT, L.P. | 1.9% | 1,246,456 | 1.3% | $107,793,515 | |
| Vestal Point Capital, LP | 1.6% | 1,100,000 | +2.3% | 4.3% | $95,128,000 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.6% | 1,093,993 | +9.7% | 0.01% | $94,623,097 |
| Woodline Partners LP | 1.6% | 1,069,520 | +18% | 0.44% | $92,492,090 |
| Polar Capital Holdings Plc | 1.5% | 1,022,225 | +25% | 0.43% | $88,402,018 |
| T. Rowe Price Investment Management, Inc. | 1.5% | 1,021,236 | -6.7% | 0.05% | $88,317,000 |
| BRAIDWELL LP | 1.5% | 1,012,982 | -14% | 2.6% | $87,602,683 |
| Fairmount Funds Management LLC | 1.1% | 727,563 | 0% | 5.7% | $62,919,648 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 0.86% | 574,500 | -0.52% | 0.08% | $49,682,760 |
| AMERIPRISE FINANCIAL INC | 0.79% | 527,050 | +8.8% | 0.01% | $45,579,378 |
| GOLDMAN SACHS GROUP INC | 0.67% | 444,436 | -17% | 0.01% | $38,434,825 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.61% | 404,553 | +17% | 0.01% | $34,985,743 |
| First Turn Management, LLC | 0.59% | 394,754 | +23% | 5.1% | $34,138,326 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 226,068 | $22,741,198 | +$9,622,752 | $100.59 | 16 |
| 2025 Q3 | 72,412,845 | $6,262,252,861 | +$70,662,102 | $86.48 | 194 |
| 2025 Q2 | 71,891,483 | $5,485,539,377 | +$5,743,561 | $76.30 | 208 |
| 2025 Q1 | 71,880,102 | $5,100,674,966 | +$85,199,094 | $70.92 | 203 |
| 2024 Q4 | 70,585,260 | $5,525,398,157 | -$80,588,060 | $78.28 | 215 |
| 2024 Q3 | 69,868,644 | $7,146,221,896 | +$390,882,960 | $102.30 | 195 |
| 2024 Q2 | 65,593,290 | $4,976,283,368 | +$173,022,836 | $75.86 | 173 |
| 2024 Q1 | 63,313,813 | $4,754,678,467 | -$14,862,514 | $75.09 | 180 |
| 2023 Q4 | 98,207 | $7,244,073 | +$6,535,401 | $74.33 | 2 |
| 2023 Q3 | 55,841,595 | $2,567,110,930 | +$27,221,591 | $45.97 | 113 |
| 2023 Q2 | 55,250,193 | $2,329,915,838 | +$51,032,078 | $42.17 | 106 |
| 2023 Q1 | 54,098,142 | $1,410,654,537 | +$30,165,458 | $26.09 | 86 |
| 2022 Q4 | 52,899,571 | $1,575,387,675 | +$247,034,531 | $29.78 | 93 |
| 2022 Q3 | 45,201,103 | $878,744,433 | -$4,772,019 | $19.44 | 59 |
| 2022 Q2 | 45,838,310 | $621,596,308 | +$7,918,329 | $13.56 | 52 |
| 2022 Q1 | 45,261,264 | $628,629,401 | +$29,987,990 | $13.89 | 54 |
| 2021 Q4 | 43,000,522 | $813,075,968 | +$11,850,957 | $19.04 | 49 |
| 2021 Q3 | 42,365,809 | $941,242,049 | +$941,242,034 | $22.55 | 47 |