Sionna Therapeutics, Inc. - Common Stock, $0.001 par value per share (SION)

Historical Holders from Q1 2025 to Q4 2025

Type / Class
Equity / Common Stock, $0.001 par value per share
Symbol
SION on Nasdaq
Shares outstanding
44,565,097
Price per share
$41.15
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
42,840,564
Total reported value
$1,259,943,482
% of total 13F portfolios
0%
Share change
-608,448
Value change
-$14,718,335
Number of holders
78
Price from insider filings
$41.15
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Sionna Therapeutics, Inc. - Common Stock, $0.001 par value per share (SION) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
RA CAPITAL MANAGEMENT, L.P. 23% -4.6% $296,218,114 -$10,988,206 10,071,712 -3.6% RA Capital Management, L.P. 05 Nov 2025
TPG GP A, LLC 15% $51,206,809 6,684,962 TPG GP A, LLC 10 Feb 2025
ORBIMED ADVISORS LLC 8.4% $28,379,986 3,704,959 ORBIMED ADVISORS LLC 10 Feb 2025
VIKING GLOBAL INVESTORS LP 6.7% $22,618,096 2,952,754 VIKING GLOBAL INVESTORS LP 10 Feb 2025
Enavate Sciences GP, LLC 5.6% $18,981,710 2,478,030 Enavate Sciences GP, LLC 10 Feb 2025
Atlas Venture Fund XI, L.P. 5.4% -16% $74,745,063 -$15,805,453 2,382,495 -17% Atlas Venture Fund XI, L.P. 16 Oct 2025
Qatar Investment Authority 5% $28,351,413 2,209,775 Qatar Investment Authority 11 Jun 2025
JPMORGAN CHASE & CO 4.4% -12% $58,251,993 -$7,075,145 1,980,626 -11% JPMORGAN CHASE & CO. 30 Sep 2025
As of 30 Sep 2025, Sionna Therapeutics, Inc. - Common Stock, $0.001 par value per share (SION) has 78 institutional shareholders filing 13F forms. They hold 42,840,564 shares. of 44,565,097 outstanding shares (96%) .

Top 25 institutional shareholders own 94% of the company.

Filer Ownership Nb Shares Share Change % Portfolio % Holdings Value
RA CAPITAL MANAGEMENT, L.P. 23% 10,445,322 0% 3.8% $307,196,920
TPG GP A, LLC 15% 6,744,962 0% 11% $198,369,332
ORBIMED ADVISORS LLC 8.3% 3,704,959 0% 2.6% $108,962,844
Atlas Venture Life Science Advisors, LLC 8.1% 3,615,527 -2.1% 14% $106,332,649
VIKING GLOBAL INVESTORS LP 7.2% 3,195,181 0% 0.24% $93,970,273
ENAVATE SCIENCES GP, LLC 5.6% 2,478,030 0% 22% $72,878,862
JPMORGAN CHASE & CO 4.4% 1,978,626 -11% 0% $58,191,390
PERCEPTIVE ADVISORS LLC 2.6% 1,179,098 -3% 1% $34,677,272
VANGUARD GROUP INC 2.6% 1,143,154 +81% 0% $33,620,159
JENNISON ASSOCIATES LLC 2.2% 997,375 +32% 0.02% $29,332,799
DEERFIELD MANAGEMENT COMPANY, L.P. 2.2% 970,590 0% 0.44% $28,545,052
Aberdeen Group plc 2.1% 950,547 0% 0.04% $27,955,587
BlackRock, Inc. 1.9% 844,605 +33% 0% $24,839,832
PRICE T ROWE ASSOCIATES INC /MD/ 1.4% 637,760 -26% 0% $18,757,000
Soleus Capital Management, L.P. 0.93% 413,500 +10% 0.65% $12,161,035
BAKER BROS. ADVISORS LP 0.9% 400,000 0% 0.09% $11,764,000
Siren, L.L.C. 0.73% 325,000 0% 0.37% $9,558,250
GEODE CAPITAL MANAGEMENT, LLC 0.71% 316,564 +9.4% 0% $9,311,794
BRAIDWELL LP 0.7% 314,013 -71% 0.27% $9,235,122
FRANKLIN RESOURCES INC 0.54% 242,147 -52% 0% $7,121,543
STATE STREET CORP 0.54% 240,199 +93% 0% $7,064,253
MILLENNIUM MANAGEMENT LLC 0.48% 214,085 +1425% 0% $6,296,240
Alyeska Investment Group, L.P. 0.42% 186,222 0% 0.02% $5,476,789
AMERIPRISE FINANCIAL INC 0.34% 153,151 -35% 0% $4,504,171
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.25% 111,496 +20% 0% $3,279,097

Institutional Holders of Sionna Therapeutics, Inc. - Common Stock, $0.001 par value per share (SION) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price Investors
2025 Q4 10,868 $447,282 +$440,987 $41.15 2
2025 Q3 42,840,564 $1,259,943,482 -$14,718,335 $29.41 78
2025 Q2 43,448,393 $753,831,077 +$37,292,996 $17.35 65
2025 Q1 41,491,947 $434,056,422 +$434,056,390 $10.46 47