SOLENO THERAPEUTICS INC - Common Stock, $0.001 par value per share (SLNO)

Historical Holders from Q3 2022 to Q4 2025

Type / Class
Equity / Common Stock, $0.001 par value per share
Symbol
SLNO on Nasdaq
Shares outstanding
53,599,048
Price per share
$46.30
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares as of 30 Sep 2025
65,164,479
Holdings value
$4,403,299,841
% of all portfolios
0.01%
Share change
+8,419,648
Value change
+$507,165,717
Average buys %
+0%
Average sells %
-0.01%
Number of holders
235
Price from insider filings
$49.95
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of SOLENO THERAPEUTICS INC - Common Stock, $0.001 par value per share (SLNO) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
FMR LLC 15% +120% $597,403,881 +$342,858,859 7,833,778 +135% FMR LLC 31 Jul 2025
JANUS HENDERSON GROUP PLC 11% +8.2% $409,408,516 +$50,587,108 6,056,339 +14% JANUS HENDERSON GROUP PLC 30 Sep 2025
PRICE T ROWE ASSOCIATES INC /MD/ 6.9% +34% $236,801,899 +$72,563,992 3,461,510 +44% T. Rowe Price Associates, Inc. 30 Jun 2025
VANGUARD GROUP INC 5.3% $189,763,272 2,807,149 The Vanguard Group 30 Sep 2025
ADAGE CAPITAL PARTNERS GP, L.L.C. 6.4% $175,636,002 2,775,976 Adage Capital Management, L.P. 31 Dec 2024
BlackRock, Inc. 5.5% +16% $210,952,318 +$57,685,733 2,766,225 +38% BlackRock, Inc. 30 Jun 2025
Vivo Opportunity Fund Holdings, L.P. 4.2% -46% $152,178,416 -$115,402,258 2,251,160 -43% Vivo Opportunity Fund Holdings, L.P. 30 Sep 2025
Avoro Capital Advisors LLC 4.1% $140,240,500 2,050,000 Avoro Capital Advisors LLC 30 Jun 2025
Adage Capital Management, L.P. 2.6% -64% $94,746,538 -$146,988,629 1,401,576 -61% Adage Capital Management, L.P. 30 Sep 2025
Nantahala Capital Management, LLC 2% -60% $68,502,354 -$111,255,251 1,001,350 -62% Nantahala Capital Management, LLC 30 Jun 2025
As of 30 Sep 2025, SOLENO THERAPEUTICS INC - Common Stock, $0.001 par value per share (SLNO) has 235 institutional shareholders filing 13F forms. They hold 65,164,479 shares .

Top 25 institutional shareholders own 92% of the company.

Filer Ownership Nb Shares Share Change % Portfolio % Holdings Value
FMR LLC 15% 7,999,682 +140% 0.03% $540,778,476
JANUS HENDERSON GROUP PLC 11% 6,056,339 +14% 0.19% $409,496,314
PRICE T ROWE ASSOCIATES INC /MD/ 7.3% 3,902,906 +13% 0.03% $263,837,000
BlackRock, Inc. 6.5% 3,492,252 +23% 0% $236,076,235
VANGUARD GROUP INC 5.2% 2,807,149 +13% 0% $189,763,272
Avoro Capital Advisors LLC 4.8% 2,577,777 +26% 2.3% $174,257,725
WELLINGTON MANAGEMENT GROUP LLP 4.3% 2,312,095 +272% 0.03% $156,297,621
Vivo Capital, LLC 4.3% 2,278,203 -42% 12% $154,006,523
STATE STREET CORP 4.1% 2,173,036 +55% 0.01% $146,897,234
Invesco Ltd. 2.8% 1,500,525 +132% 0.02% $101,435,491
ADAGE CAPITAL PARTNERS GP, L.L.C. 2.6% 1,401,576 -61% 0.15% $94,746,538
Commodore Capital LP 2.5% 1,350,000 +121% 4.5% $91,260,000
BRAIDWELL LP 2.4% 1,281,989 2.6% $86,662,456
Polar Capital Holdings Plc 2.2% 1,191,123 +46% 0.39% $80,519,915
GEODE CAPITAL MANAGEMENT, LLC 2% 1,084,952 +20% 0% $73,355,617
Holocene Advisors, LP 1.9% 997,069 -14% 0.15% $67,401,864
MILLENNIUM MANAGEMENT LLC 1.8% 979,826 +55% 0.05% $66,236,238
WESTFIELD CAPITAL MANAGEMENT CO LP 1.7% 899,157 -37% 0.26% $60,783,013
Nantahala Capital Management, LLC 1.6% 863,763 -14% 3.6% $58,390,379
FRANKLIN RESOURCES INC 1.6% 835,751 +348% 0.01% $56,496,747
Capital World Investors 1.5% 824,514 +34% 0.01% $55,737,146
Artia Global Partners LP 1.3% 672,176 +36% 8% $45,439,098
Balyasny Asset Management L.P. 1.2% 660,565 +83% 0.09% $44,654,194
EMERALD ADVISERS, LLC 1.2% 627,756 -6.7% 1.4% $42,436,306
Bank of New York Mellon Corp 1.2% 627,227 +29% 0.01% $42,400,563

Institutional Holders of SOLENO THERAPEUTICS INC - Common Stock, $0.001 par value per share (SLNO) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price Investors
2025 Q4 424,638 $19,660,572 +$18,963,170 $46.30 5
2025 Q3 65,164,479 $4,403,299,841 +$507,165,717 $67.60 235
2025 Q2 56,749,470 $4,754,316,405 +$213,454,333 $83.78 231
2025 Q1 54,568,286 $3,901,553,813 +$304,734,981 $71.45 215
2024 Q4 51,039,620 $2,293,785,053 +$169,955,348 $44.95 164
2024 Q3 47,119,847 $2,378,750,520 +$200,219,936 $50.49 141
2024 Q2 43,316,980 $1,767,677,409 +$339,229,097 $40.80 112
2024 Q1 34,986,278 $1,496,099,350 +$151,053,440 $42.80 100
2023 Q4 31,409,972 $1,264,282,974 +$428,153,179 $40.25 76
2023 Q3 20,301,195 $598,794,549 +$451,363,845 $29.51 54
2023 Q2 4,852,710 $20,757,863 +$7,837,297 $4.29 22
2023 Q1 3,071,637 $6,538,076 +$3,161,390 $2.14 20
2022 Q4 2,785,956 $5,517,109 +$81,616 $1.98 22
2022 Q3 2,780,768 $4,643,586 +$4,627,984 $1.67 12