Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2018 to Q4 2025

Type / Class
Equity / Common stock, $0.00001 par value per share
Symbol
TWST on Nasdaq
Shares outstanding
60,389,334
Price per share
$31.72
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
73,760,956
Total reported value
$2,075,454,827
% of total 13F portfolios
0%
Share change
+2,570,061
Value change
+$57,819,067
Number of holders
233
Price from insider filings
$31.72
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Artisan Partners Limited Partnership 11% +28% $180,403,367 +$37,985,392 6,410,900 +27% Artisan Partners Asset Management Inc. 30 Sep 2025
ARK Investment Management LLC 11% +17% $230,970,588 +$37,061,202 6,382,166 +19% ARK Investment Management LLC 28 Feb 2025
BlackRock, Inc. 8.3% $178,335,272 4,927,750 BlackRock, Inc. 31 Mar 2025
EdgePoint Investment Group Inc. 6.8% $114,876,457 4,082,319 EdgePoint Investment Group Inc. 30 Sep 2025
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 6.4% +28% $137,770,517 +$31,020,041 3,806,867 +29% WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 31 Mar 2025
STATE STREET CORP 5.1% +20% $86,926,233 +$15,338,157 3,089,063 +21% STATE STREET CORPORATION 30 Sep 2025
Invesco Ltd. 3.9% $88,540,403 2,347,929 Invesco Ltd. 30 Jun 2025

As of 30 Sep 2025, 233 institutional investors reported holding 73,760,956 shares of Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST). This represents 122% of the company’s total 60,389,334 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST) together control 100% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
ARK Investment Management LLC 11% 6,726,808 +5.1% 1.1% $189,292,386
Artisan Partners Limited Partnership 11% 6,410,900 +27% 0.26% $180,402,726
BlackRock, Inc. 10% 6,178,376 -1.6% 0% $173,859,502
VANGUARD GROUP INC 9.6% 5,768,149 -1.1% 0% $162,315,713
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 6.9% 4,142,283 +6% 0.3% $116,563,844
EdgePoint Investment Group Inc. 6.8% 4,082,319 +71% 0.86% $114,876,457
STATE STREET CORP 5.1% 3,089,063 +24% 0% $86,926,233
Sumitomo Mitsui Trust Group, Inc. 3.5% 2,120,206 -7.8% 0.03% $59,662,597
Amova Asset Management Americas, Inc. 3.5% 2,120,206 -7.8% 0.58% $59,641,395
Soleus Capital Management, L.P. 3.1% 1,866,234 +427% 2.8% $52,515,825
Invesco Ltd. 3% 1,795,143 -24% 0.01% $50,515,324
MILLENNIUM MANAGEMENT LLC 3% 1,793,850 +152% 0.04% $50,478,939
GOLDMAN SACHS GROUP INC 2.7% 1,627,020 +6.7% 0.01% $45,784,343
MORGAN STANLEY 2.5% 1,492,106 +24% 0% $41,987,888
Thrivent Financial for Lutherans 2.4% 1,463,085 +14% 0.08% $41,171,000
GEODE CAPITAL MANAGEMENT, LLC 2.4% 1,448,413 +1.7% 0% $40,764,323
BAILLIE GIFFORD & CO 2.1% 1,262,739 +63% 0.03% $35,533,475
First Light Asset Management, LLC 2% 1,194,883 +26% 3.2% $33,624,008
UBS AM, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS LLC 1.9% 1,123,697 -7.8% 0.01% $31,620,833
JPMORGAN CHASE & CO 1.7% 1,018,234 -29% 0% $28,653,105
AMERICAN CENTURY COMPANIES INC 1.4% 838,064 -3% 0.01% $23,583,186
Tao Capital Management LP 1.4% 828,815 0% 18% $23,322,854
DIMENSIONAL FUND ADVISORS LP 1.3% 790,893 +8.6% 0% $22,252,035
JENNISON ASSOCIATES LLC 1.1% 634,600 +2.6% 0.01% $17,857,642
NEW YORK STATE COMMON RETIREMENT FUND 0.97% 584,694 +14% 0.02% $16,453,289

Institutional Holders of Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 77,115 $2,446,015 +$1,894,529 $31.72 4
2025 Q3 73,760,956 $2,075,454,827 +$57,819,067 $28.14 233
2025 Q2 71,133,390 $2,616,814,853 +$58,445,653 $36.79 240
2025 Q1 69,532,083 $2,729,868,571 +$98,718,268 $39.26 260
2024 Q4 66,354,665 $3,083,194,982 +$14,661,464 $46.47 243
2024 Q3 65,889,652 $2,978,632,352 -$19,242,374 $45.18 239
2024 Q2 65,973,644 $3,251,114,144 +$42,220,565 $49.28 258
2024 Q1 66,798,067 $2,291,666,266 +$23,086,641 $34.31 229
2023 Q4 22,653 $834,990 -$324,656 $36.86 1
2023 Q3 66,013,247 $1,337,392,715 -$31,189,675 $20.26 188
2023 Q2 67,748,621 $1,386,120,001 +$101,069,312 $20.46 182
2023 Q1 63,476,335 $956,236,086 +$12,786,268 $15.08 194
2022 Q4 60,659,342 $1,444,177,405 +$141,337,882 $23.81 185
2022 Q3 54,691,464 $1,915,406 -$67,544,565 $0.04 196
2022 Q2 53,439,104 $1,849,186,166 -$79,088,191 $34.96 179
2022 Q1 59,105,909 $2,908,525,208 +$350,228,550 $49.38 191
2021 Q4 51,095,575 $3,947,638,776 +$149,694,676 $77.39 218
2021 Q3 48,639,354 $5,192,963,091 +$44,162,011 $106.97 229
2021 Q2 48,098,479 $6,397,676,299 +$162,838,381 $133.25 235
2021 Q1 46,893,465 $5,808,669,841 +$482,976,075 $123.86 230
2020 Q4 42,890,429 $6,060,093,051 +$546,176,364 $141.29 209
2020 Q3 39,702,212 $3,017,973,941 +$218,818,669 $75.97 189
2020 Q2 33,433,884 $1,513,032,837 +$271,060,356 $45.30 139
2020 Q1 30,332,035 $928,048,817 +$329,101,082 $30.58 113
2019 Q4 19,631,017 $412,249,368 +$39,746,513 $21.00 91
2019 Q3 15,594,559 $372,395,352 +$36,200,127 $23.88 80
2019 Q2 13,841,506 $399,807,564 +$229,954,622 $29.01 81
2019 Q1 6,002,180 $137,676,000 -$1,670,476 $23.18 46
2018 Q4 6,075,941 $137,391,000 +$137,391,088 $23.09 45