| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| FMR LLC | 8.3% | $239,585,319 | 7,964,937 | FMR LLC | 30 Sep 2025 | |||
| BlackRock, Inc. | 5.1% | $163,140,305 | 4,820,931 | BlackRock, Inc. | 31 Mar 2025 | |||
| SANDS CAPITAL MANAGEMENT, LLC | 4.7% | $145,444,422 | 4,298,003 | SANDS CAPITAL MANAGEMENT, LLC | 31 Dec 2024 | |||
| WELLINGTON MANAGEMENT GROUP LLP | 2.7% | $83,163,255 | 2,457,543 | Wellington Management Group LLP | 31 Dec 2024 |
As of 30 Sep 2025, 295 institutional investors reported holding 95,477,293 shares of Ultragenyx Pharmaceutical Inc. - COMMON STOCK (RARE). This represents 99% of the company’s total 95,963,102 outstanding shares.
The largest institutional shareholders of Ultragenyx Pharmaceutical Inc. - COMMON STOCK (RARE) together control 68% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 11% | 10,132,728 | -0.79% | 0% | $304,792,459 |
| FMR LLC | 7.6% | 7,283,296 | +180% | 0.01% | $219,081,558 |
| BlackRock, Inc. | 6.7% | 6,425,263 | +2.7% | 0% | $193,271,911 |
| JPMORGAN CHASE & CO | 4.2% | 4,011,429 | +23% | 0.01% | $120,663,796 |
| SANDS CAPITAL MANAGEMENT, LLC | 3.9% | 3,769,853 | -4.4% | 0.31% | $113,397,178 |
| STATE STREET CORP | 3.8% | 3,692,487 | +44% | 0% | $111,070,009 |
| RTW INVESTMENTS, LP | 3.4% | 3,258,266 | +91% | 1.2% | $98,008,641 |
| BAKER BROS. ADVISORS LP | 2.9% | 2,772,692 | 0% | 0.6% | $83,402,575 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.4% | 2,310,174 | -20% | 0.01% | $69,491,000 |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 2.3% | 2,167,729 | +614% | 0.26% | $65,205,288 |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 2.1% | 2,019,000 | -11% | 1.8% | $60,731,520 |
| WELLINGTON MANAGEMENT GROUP LLP | 2% | 1,945,129 | +3.9% | 0.01% | $58,509,481 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.6% | 1,580,507 | -7.7% | 0% | $47,551,518 |
| DEUTSCHE BANK AG\ | 1.6% | 1,546,101 | -7.2% | 0.02% | $46,506,718 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1.6% | 1,545,279 | +6.4% | 0.12% | $46,482,000 |
| Pictet Asset Management Holding SA | 1.5% | 1,458,187 | -14% | 0.04% | $43,988,784 |
| Rock Springs Capital Management LP | 1.3% | 1,246,341 | -10% | 2.2% | $37,489,937 |
| GW&K Investment Management, LLC | 1.2% | 1,150,169 | +139% | 0.31% | $34,597,000 |
| Schonfeld Strategic Advisors LLC | 1.2% | 1,144,589 | +102% | 0.24% | $34,429,232 |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 1.1% | 1,069,098 | +103% | 0.29% | $32,158,463 |
| Frazier Life Sciences Management, L.P. | 1% | 983,715 | 0% | 0.89% | $29,590,147 |
| Aberdeen Group plc | 1% | 973,656 | +94% | 0.05% | $29,287,572 |
| MORGAN STANLEY | 0.95% | 910,183 | +42% | 0% | $27,378,343 |
| Russell Investments Group, Ltd. | 0.88% | 840,451 | +599% | 0.03% | $25,280,799 |
| Invesco Ltd. | 0.83% | 794,849 | +9.8% | 0% | $23,909,058 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 408,423 | $9,355,703 | -$4,292,412 | $23.00 | 10 |
| 2025 Q3 | 95,477,293 | $2,872,224,808 | -$30,046,998 | $30.08 | 295 |
| 2025 Q2 | 94,131,376 | $3,423,160,510 | +$191,188,594 | $36.36 | 307 |
| 2025 Q1 | 88,841,761 | $3,218,912,230 | +$30,616,545 | $36.21 | 296 |
| 2024 Q4 | 87,497,812 | $3,681,153,647 | +$41,521,385 | $42.07 | 309 |
| 2024 Q3 | 85,955,607 | $4,772,717,045 | -$110,532,026 | $55.55 | 302 |
| 2024 Q2 | 88,188,346 | $3,624,602,754 | +$370,533,398 | $41.10 | 271 |
| 2024 Q1 | 79,126,955 | $3,691,777,497 | -$57,749,656 | $46.69 | 271 |
| 2023 Q4 | 254,995 | $12,200,616 | +$675,667 | $47.82 | 4 |
| 2023 Q3 | 69,998,943 | $2,495,206,751 | +$11,050,478 | $35.65 | 217 |
| 2023 Q2 | 68,829,326 | $3,174,706,065 | +$15,102,181 | $46.13 | 234 |
| 2023 Q1 | 68,644,414 | $2,752,282,615 | +$26,131,494 | $40.10 | 223 |
| 2022 Q4 | 67,934,602 | $3,146,859,962 | +$17,186,181 | $46.33 | 219 |
| 2022 Q3 | 61,623,095 | $2,551,540,992 | -$145,131,092 | $41.41 | 212 |
| 2022 Q2 | 62,104,100 | $3,704,244,142 | +$18,551,491 | $59.66 | 202 |
| 2022 Q1 | 61,754,989 | $4,483,460,176 | -$41,802,077 | $72.62 | 218 |
| 2021 Q4 | 67,334,441 | $5,662,132,194 | +$81,983,266 | $84.09 | 215 |
| 2021 Q3 | 66,612,239 | $6,007,303,733 | +$102,035,423 | $90.19 | 213 |
| 2021 Q2 | 65,392,463 | $6,231,602,585 | -$249,392,464 | $95.35 | 232 |
| 2021 Q1 | 67,846,874 | $7,727,265,104 | +$49,991,404 | $113.86 | 249 |
| 2020 Q4 | 67,545,737 | $9,350,737,606 | +$638,585,678 | $138.43 | 244 |
| 2020 Q3 | 63,072,100 | $5,185,727,312 | -$1,949,481 | $82.19 | 195 |
| 2020 Q2 | 63,110,521 | $4,936,928,777 | +$247,643,422 | $78.22 | 182 |
| 2020 Q1 | 60,099,983 | $2,669,904,425 | +$85,612,131 | $44.43 | 162 |
| 2019 Q4 | 55,205,870 | $2,358,324,671 | -$33,639,501 | $42.71 | 160 |
| 2019 Q3 | 55,702,426 | $2,382,914,127 | -$47,549,611 | $42.78 | 158 |
| 2019 Q2 | 58,716,843 | $3,728,145,996 | +$71,705,781 | $63.50 | 161 |
| 2019 Q1 | 58,008,421 | $4,023,373,718 | +$543,100,082 | $69.36 | 168 |
| 2018 Q4 | 50,549,541 | $2,197,742,355 | -$8,885,210 | $43.48 | 154 |
| 2018 Q3 | 49,753,300 | $3,798,512,508 | +$72,495,762 | $76.34 | 170 |
| 2018 Q2 | 48,810,127 | $3,751,956,303 | +$80,184,864 | $76.87 | 150 |
| 2018 Q1 | 48,901,336 | $2,493,446,451 | +$367,115,489 | $50.99 | 158 |
| 2017 Q4 | 43,222,558 | $2,004,746,148 | +$107,321,290 | $46.38 | 154 |
| 2017 Q3 | 40,572,315 | $2,163,180,778 | -$37,010,406 | $53.26 | 146 |
| 2017 Q2 | 41,008,853 | $2,542,280,579 | +$29,525,098 | $62.11 | 150 |
| 2017 Q1 | 40,482,016 | $2,743,172,220 | +$147,351,890 | $67.78 | 157 |
| 2016 Q4 | 41,216,638 | $2,897,963,973 | +$148,715,174 | $70.31 | 168 |
| 2016 Q3 | 39,487,317 | $2,799,413,760 | +$185,324,978 | $70.94 | 164 |
| 2016 Q2 | 36,359,644 | $1,778,407,912 | -$45,265,344 | $48.91 | 152 |
| 2016 Q1 | 36,539,252 | $2,312,703,412 | +$79,826,584 | $63.31 | 153 |
| 2015 Q4 | 35,576,350 | $3,991,055,622 | +$41,273,420 | $112.18 | 164 |
| 2015 Q3 | 34,876,655 | $3,359,085,001 | +$212,205,502 | $96.31 | 154 |
| 2015 Q2 | 32,244,569 | $3,302,070,876 | +$99,906,036 | $102.39 | 147 |
| 2015 Q1 | 31,562,838 | $1,958,899,846 | +$230,197,763 | $62.09 | 124 |
| 2014 Q4 | 27,930,073 | $1,225,534,642 | +$58,843,940 | $43.88 | 99 |
| 2014 Q3 | 26,448,763 | $1,496,999,849 | +$358,139,148 | $56.60 | 98 |
| 2014 Q2 | 15,622,329 | $689,540,361 | +$13,828,526 | $44.89 | 80 |
| 2014 Q1 | 15,337,936 | $730,185,000 | +$729,725,256 | $48.89 | 76 |