| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| CITADEL ADVISORS LLC | 0% | -103% | $1,238 | -$363,632 | 3,732 | -100% | Kenneth Griffin | 30 Sep 2025 |
As of 30 Sep 2025, 31 institutional investors reported holding 3,924,005 shares of VYNE Therapeutics Inc. - Common Stock, par value $0.0001 per share (VYNE). This represents 24% of the company’s total 16,657,813 outstanding shares.
The largest institutional shareholders of VYNE Therapeutics Inc. - Common Stock, par value $0.0001 per share (VYNE) together control 24% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 5.1% | 851,353 | 0% | $285,203 | |
| ACORN CAPITAL ADVISORS, LLC | 3.5% | 586,572 | -20% | 0.1% | $199,434 |
| Shay Capital LLC | 3% | 492,577 | 0.03% | $165,013 | |
| ACADIAN ASSET MANAGEMENT LLC | 2.7% | 446,414 | +1891% | 0% | $148,000 |
| Ikarian Capital, LLC | 1.7% | 290,000 | 0% | 0.02% | $97,149 |
| TWO SIGMA INVESTMENTS, LP | 1.3% | 220,788 | 0% | $73,964 | |
| VANGUARD GROUP INC | 1.1% | 190,383 | -62% | 0% | $63,778 |
| JANE STREET GROUP, LLC | 0.88% | 147,120 | +18% | 0% | $49,285 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.82% | 137,122 | +2.8% | 0% | $45,938 |
| BOOTHBAY FUND MANAGEMENT, LLC | 0.64% | 106,459 | 0% | 0% | $35,664 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0.46% | 76,958 | 0% | 0% | $25,781 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.35% | 57,763 | -0.09% | 0% | $19,351 |
| TWO SIGMA ADVISERS, LP | 0.34% | 56,600 | 0% | $18,961 | |
| Rangeley Capital, LLC | 0.3% | 50,000 | 0.02% | $16,750 | |
| CORSAIR CAPITAL MANAGEMENT, L.P. | 0.3% | 50,000 | +400% | 0% | $16,750 |
| BlackRock, Inc. | 0.27% | 44,404 | -0% | 0% | $14,875 |
| GSA CAPITAL PARTNERS LLP | 0.22% | 35,921 | +167% | 0% | $12,000 |
| NORTHERN TRUST CORP | 0.14% | 23,110 | 0% | 0% | $7,742 |
| COMMONWEALTH EQUITY SERVICES, LLC | 0.11% | 18,298 | 0% | 0% | $6,000 |
| STATE STREET CORP | 0.09% | 15,765 | 0% | 0% | $5,281 |
| Harvest Investment Services, LLC | 0.07% | 11,059 | -78% | 0% | $3,705 |
| UBS Group AG | 0.03% | 5,572 | 0% | $1,866 | |
| Tower Research Capital LLC (TRC) | 0.02% | 3,597 | +28% | 0% | $1,205 |
| ROYAL BANK OF CANADA | 0.01% | 2,440 | 0% | 0% | $1,000 |
| BANK OF AMERICA CORP /DE/ | 0.01% | 1,532 | +4.3% | 0% | $513 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 3,924,005 | $1,315,944 | -$9,032,758 | $0.34 | 31 |
| 2025 Q2 | 8,048,768 | $13,279,291 | +$1,503,900 | $1.65 | 44 |
| 2025 Q1 | 7,109,939 | $11,401,092 | -$2,382,241 | $1.58 | 36 |
| 2024 Q4 | 7,028,274 | $23,320,995 | +$606,162 | $3.35 | 34 |
| 2024 Q3 | 7,311,514 | $14,254,945 | -$1,226,340 | $1.88 | 30 |
| 2024 Q2 | 7,941,245 | $16,028,242 | +$243,084 | $1.97 | 29 |
| 2024 Q1 | 6,404,045 | $19,659,953 | +$378,441 | $3.07 | 28 |
| 2023 Q4 | 1,041 | $2,426 | $2.33 | 1 | |
| 2023 Q3 | 359,058 | $1,441,664 | -$33,735 | $4.04 | 19 |
| 2023 Q2 | 374,919 | $1,528,118 | +$203,281 | $4.10 | 18 |
| 2023 Q1 | 334,218 | $1,028,742 | +$1,028,744 | $3.08 | 18 |