Zymeworks Inc. - Common Stock (ZYME)

Historical Holders from Q3 2022 to Q4 2025

Type / Class
Equity / Common Stock
Symbol
ZYME on Nasdaq
Shares outstanding
74,822,111
Price per share
$26.33
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares as of 30 Sep 2025
73,699,594
Total reported value
$1,258,820,490
% of total 13F portfolios
0%
Share change
-2,160,232
Value change
-$22,883,482
Avg buy value change
+0%
Avg sell value change
-0%
Number of holders
181
Price from insider filings
$10.55
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Zymeworks Inc. - Common Stock (ZYME) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
EcoR1 Capital, LLC 31% 0% $420,817,508 22,970,388 0% EcoR1 Capital, LLC 16 Nov 2025
MORGAN STANLEY 5.8% $48,337,650 4,055,172 Morgan Stanley 31 Mar 2025
BIOTECHNOLOGY VALUE FUND L P 5.2% $67,271,988 3,938,641 BVF PARTNERS L P/IL 30 Sep 2025
Redmile Group, LLC 4.9% -12% $63,294,210 -$7,598,499 3,705,750 -11% Redmile Group, LLC 30 Sep 2025
BlackRock, Inc. 4.8% $40,261,655 3,559,828 BlackRock, Inc. 30 Jun 2025
As of 30 Sep 2025, Zymeworks Inc. - Common Stock (ZYME) has 181 institutional shareholders filing 13F forms. They hold 73,699,594 shares of 74,822,111 outstanding shares (98%) .

Top 25 institutional shareholders own 87% of the company.

Filer Ownership Nb Shares Share Change % Portfolio % Holdings Value
EcoR1 Capital, LLC 31% 22,970,388 0% 19% $392,334,227
Rubric Capital Management LP 6.3% 4,710,551 0% 1.1% $80,456,211
BlackRock, Inc. 5.3% 3,989,533 +5.1% 0% $68,141,224
MORGAN STANLEY 5.3% 3,984,585 -4.6% 0% $68,056,714
BVF INC/IL 5.3% 3,938,641 -8.6% 2.7% $67,271,988
Redmile Group, LLC 5% 3,705,750 -11% 6.2% $63,294,210
VANGUARD GROUP INC 2.9% 2,154,434 -13% 0% $36,797,732
PERCEPTIVE ADVISORS LLC 2.8% 2,090,663 +64% 1% $35,708,524
Vestal Point Capital, LP 2.4% 1,765,000 +53% 1.4% $30,146,200
UBS AM, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS LLC 2.3% 1,710,463 -30% 0.01% $29,214,708
Blackstone Inc. 2.2% 1,616,290 -2.4% 0.12% $27,606,233
DEUTSCHE BANK AG\ 2.1% 1,544,898 +0.01% 0.01% $26,386,859
Assenagon Asset Management S.A. 1.8% 1,326,774 +169% 0.03% $22,661,300
DIMENSIONAL FUND ADVISORS LP 1.6% 1,190,838 -0.13% 0% $20,340,605
Nextech Invest, Ltd. 1.5% 1,113,946 0% 2.9% $19,026,198
MILLENNIUM MANAGEMENT LLC 1.5% 1,104,813 +852% 0.01% $18,870,206
TANG CAPITAL MANAGEMENT LLC 1.5% 1,100,000 0% 0.72% $18,788,000
STATE STREET CORP 1.4% 1,081,189 -0.67% 0% $18,466,708
Prosight Management, LP 1% 749,611 -43% 3.1% $12,803,356
GEODE CAPITAL MANAGEMENT, LLC 0.91% 678,636 -3.8% 0% $11,590,695
Nuveen, LLC 0.76% 565,385 -14% 0% $9,656,776
ADAGE CAPITAL PARTNERS GP, L.L.C. 0.75% 564,000 +18% 0.02% $9,633,120
GOLDMAN SACHS GROUP INC 0.59% 443,525 +3.4% 0% $7,575,407
RENAISSANCE TECHNOLOGIES LLC 0.58% 431,700 -19% 0.01% $7,373,436
JUPITER ASSET MANAGEMENT LTD 0.47% 350,660 -5.1% 0.05% $5,989,273

Institutional Holders of Zymeworks Inc. - Common Stock (ZYME) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (% of par) Investors
2025 Q4 665,974 $17,534,820 -$17,780,369 2,633% 4
2025 Q3 73,699,594 $1,258,820,490 -$22,883,482 1,708% 181
2025 Q2 75,621,323 $949,023,010 +$68,009,455 1,255% 179
2025 Q1 70,389,436 $838,494,071 +$42,500,929 1,191% 182
2024 Q4 66,481,090 $973,230,338 +$2,706,239 1,464% 171
2024 Q3 66,300,575 $832,170,959 -$17,050,036 1,255% 160
2024 Q2 68,188,360 $580,316,426 +$18,235,540 851% 160
2024 Q1 67,535,154 $710,428,020 +$26,795,124 1,052% 165
2023 Q4 22,088 $229,494 1,039% 1
2023 Q3 62,178,772 $394,303,435 -$8,784,329 634% 135
2023 Q2 63,418,288 $547,947,947 +$55,584,837 864% 135
2023 Q1 56,707,830 $512,639,046 +$19,860,527 904% 113
2022 Q4 55,061,050 $432,778,373 +$428,425,541 786% 88
2022 Q3 78,394 $482,000 +$481,998 614.84% 1