| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Soleus Capital Master Fund, L.P. | 8.6% | +40% | $124,611,746 | +$35,408,164 | 9,644,872 | +39.7% | Soleus Capital Master Fund, L.P. | 30 Sep 2025 |
| BlackRock, Inc. | 8.3% | $161,870,108 | 9,083,620 | BlackRock, Inc. | 31 Mar 2025 | |||
| Capital World Investors | 1.8% | -65% | $25,840,000 | -$56,626,396 | 2,000,000 | -68.7% | Capital World Investors | 30 Sep 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 91,742,662 | $1,185,376,041 | -$65,862,677 | $12.92 | 242 |
| 2025 Q2 | 94,465,807 | $1,681,500,579 | -$12,863,877 | $17.8 | 238 |
| 2025 Q1 | 95,188,552 | $1,696,317,393 | +$20,032,634 | $17.82 | 224 |
| 2024 Q4 | 91,569,880 | $2,728,867,320 | -$6,541,149 | $29.8 | 236 |
| 2024 Q3 | 92,870,656 | $1,451,669,248 | -$11,382,332 | $15.63 | 220 |
| 2024 Q2 | 92,921,141 | $1,591,749,696 | +$79,832,472 | $17.13 | 229 |
| 2024 Q1 | 89,139,107 | $1,393,245,089 | -$23,081,055 | $15.63 | 230 |
| 2023 Q4 | 263,509 | $3,934,189 | +$1,016,833 | $14.93 | 2 |
| 2023 Q3 | 91,152,820 | $1,472,210,430 | -$63,470,630 | $16.15 | 215 |
| 2023 Q2 | 89,184,203 | $3,700,762,826 | -$22,361,797 | $41.5 | 250 |
| 2023 Q1 | 89,328,322 | $5,371,952,456 | +$289,192,883 | $60.14 | 285 |
| 2022 Q4 | 83,909,168 | $6,154,095,452 | -$12,964,425 | $73.35 | 286 |
| 2022 Q3 | 83,034,095 | $6,308,626,498 | +$222,918,594 | $75.98 | 284 |
| 2022 Q2 | 80,007,908 | $5,562,070,253 | -$38,817,221 | $69.5 | 284 |
| 2022 Q1 | 81,072,356 | $6,715,614,583 | +$237,687,782 | $82.85 | 287 |
| 2021 Q4 | 78,107,259 | $5,865,418,904 | +$31,090,849 | $75.08 | 284 |
| 2021 Q3 | 77,470,460 | $9,001,574,774 | -$79,617,117 | $116.17 | 300 |
| 2021 Q2 | 77,554,176 | $17,199,877,909 | +$681,700,760 | $221.82 | 350 |
| 2021 Q1 | 73,017,312 | $9,650,187,440 | +$117,823,846 | $132.18 | 313 |
| 2020 Q4 | 74,154,111 | $12,831,266,583 | +$246,783,732 | $173.04 | 344 |
| 2020 Q3 | 73,023,087 | $8,126,468,764 | +$543,592,499 | $111.31 | 265 |
| 2020 Q2 | 69,087,104 | $4,096,032,751 | -$79,710,864 | $59.3 | 254 |
| 2020 Q1 | 70,226,112 | $4,727,523,890 | +$67,830,767 | $67.34 | 255 |
| 2019 Q4 | 69,039,641 | $5,817,841,762 | +$164,149,700 | $84.27 | 251 |
| 2019 Q3 | 66,669,222 | $4,985,153,900 | +$91,849,435 | $74.78 | 230 |
| 2019 Q2 | 65,731,469 | $4,154,391,517 | +$248,300,371 | $63.23 | 186 |
| 2019 Q1 | 63,492,417 | $3,058,372,144 | +$301,569,077 | $48.17 | 193 |
| 2018 Q4 | 57,296,941 | $1,918,258,944 | +$53,711,292 | $33.48 | 161 |
| 2018 Q3 | 54,686,033 | $2,865,566,092 | +$201,344,784 | $52.4 | 172 |
| 2018 Q2 | 51,787,766 | $1,620,948,332 | +$282,902,138 | $31.3 | 158 |
| 2018 Q1 | 44,008,201 | $959,279,211 | +$148,499,824 | $21.8 | 131 |
| 2017 Q4 | 37,382,594 | $755,132,400 | +$13,375,574 | $20.2 | 122 |
| 2017 Q3 | 36,811,567 | $730,751,052 | +$98,792,888 | $19.85 | 101 |
| 2017 Q2 | 31,870,536 | $551,351,062 | +$204,323,240 | $17.3 | 81 |
| 2017 Q1 | 20,220,121 | $164,019,561 | +$27,081,551 | $8.1 | 66 |
| 2016 Q4 | 20,111,055 | $157,862,948 | +$10,123,034 | $7.85 | 72 |
| 2016 Q3 | 18,826,075 | $160,712,151 | -$21,761,604 | $8.54 | 61 |
| 2016 Q2 | 19,159,363 | $223,585,591 | +$67,245,761 | $11.67 | 63 |
| 2016 Q1 | 13,609,704 | $196,872,145 | +$32,309,931 | $14.48 | 55 |
| 2015 Q4 | 11,312,689 | $249,219,971 | +$248,825,091 | $22.36 | 47 |