| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| ARK Investment Management LLC | 11% | -9.1% | $634,293,720 | -$24,525,854 | 9,786,973 | -3.7% | ARK Investment Management LLC | 30 Sep 2025 |
| Capital International Investors | 7.4% | $248,931,781 | 6,334,142 | Capital International Investors | 31 Mar 2025 | |||
| BlackRock, Inc. | 6.9% | $223,000,156 | 5,932,433 | BlackRock, Inc. | 30 Jun 2025 | |||
| ORBIS INVESTMENT MANAGEMENT LTD | 5.5% | $322,373,041 | 4,974,125 | ORBIS INVESTMENT MANAGEMENT LTD | 30 Sep 2025 |
As of 30 Sep 2025, 432 institutional investors reported holding 72,231,963 shares of CRISPR Therapeutics AG - Common Stock (CRSP). This represents 80% of the company’s total 90,438,636 outstanding shares.
The largest institutional shareholders of CRISPR Therapeutics AG - Common Stock (CRSP) together control 68% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| ARK Investment Management LLC | 11% | 9,786,973 | -3.9% | 3.8% | $634,293,721 |
| BlackRock, Inc. | 7.8% | 7,050,145 | +16% | 0.01% | $456,919,897 |
| Capital International Investors | 6.2% | 5,649,258 | +0.99% | 0.06% | $366,128,411 |
| Orbis Allan Gray Ltd | 5.5% | 4,982,085 | +80% | 1.4% | $322,888,929 |
| STATE STREET CORP | 4.4% | 4,007,233 | +23% | 0.01% | $259,708,771 |
| T. Rowe Price Investment Management, Inc. | 3.6% | 3,282,584 | -11% | 0.13% | $212,745,000 |
| VANGUARD GROUP INC | 2.6% | 2,364,645 | +2.9% | 0% | $153,252,642 |
| UBS Group AG | 2.6% | 2,339,056 | -18% | 0.03% | $151,594,219 |
| Amova Asset Management Americas, Inc. | 2.4% | 2,163,675 | -10% | 1.4% | $140,184,503 |
| Sumitomo Mitsui Trust Group, Inc. | 2.4% | 2,163,675 | -10% | 0.08% | $140,227,777 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.4% | 2,141,170 | +3.3% | 0.01% | $138,790,458 |
| SR One Capital Management, LP | 2.3% | 2,038,763 | +94% | 19% | $132,132,230 |
| FMR LLC | 2.1% | 1,885,663 | -2.3% | 0.01% | $122,209,804 |
| MORGAN STANLEY | 1.5% | 1,397,859 | +173% | 0.01% | $90,595,300 |
| EcoR1 Capital, LLC | 1.5% | 1,389,276 | 0% | 4.3% | $90,038,978 |
| BANK OF AMERICA CORP /DE/ | 1.2% | 1,124,119 | -22% | 0.01% | $72,854,128 |
| NEA Management Company, LLC | 1.2% | 1,058,570 | -33% | 3.8% | $68,605,922 |
| TWO SIGMA INVESTMENTS, LP | 1.2% | 1,044,689 | -32% | 0.1% | $67,706,294 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.1% | 985,770 | +5.6% | 0.01% | $63,887,754 |
| LOOMIS SAYLES & CO L P | 1% | 909,714 | +6.2% | 0.07% | $58,958,564 |
| DIMENSIONAL FUND ADVISORS LP | 0.97% | 877,029 | -4.4% | 0.01% | $56,833,530 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.9% | 814,324 | +5.8% | 0.08% | $52,776,339 |
| NORTHERN TRUST CORP | 0.86% | 779,930 | +2.5% | 0.01% | $50,547,263 |
| JPMORGAN CHASE & CO | 0.66% | 593,416 | +85% | 0% | $38,459,291 |
| TWO SIGMA ADVISERS, LP | 0.63% | 572,972 | -57% | 0.07% | $37,134,315 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 520,326 | $27,921,660 | -$8,352,070 | $52.44 | 62 |
| 2025 Q3 | 72,231,963 | $4,680,434,967 | +$28,859,446 | $64.81 | 432 |
| 2025 Q2 | 72,314,703 | $3,517,677,257 | +$428,897,787 | $48.64 | 426 |
| 2025 Q1 | 64,127,900 | $2,183,521,222 | -$16,834,663 | $34.03 | 386 |
| 2024 Q4 | 64,437,344 | $2,536,562,743 | +$195,444,580 | $39.36 | 394 |
| 2024 Q3 | 59,414,869 | $2,791,980,873 | -$17,826,704 | $46.98 | 407 |
| 2024 Q2 | 59,498,729 | $3,213,541,420 | +$82,310,330 | $54.01 | 442 |
| 2024 Q1 | 56,692,684 | $3,864,293,150 | +$140,352,685 | $68.16 | 472 |
| 2023 Q4 | 78,463 | $4,911,785 | +$955,339 | $62.60 | 3 |
| 2023 Q3 | 54,381,899 | $2,468,918,179 | -$2,321,638 | $45.39 | 395 |
| 2023 Q2 | 54,024,280 | $3,032,144,492 | -$106,320,737 | $56.14 | 402 |
| 2023 Q1 | 56,081,743 | $2,535,451,666 | +$37,868,789 | $45.23 | 369 |
| 2022 Q4 | 55,362,530 | $2,250,234,406 | -$39,595,454 | $40.65 | 378 |
| 2022 Q3 | 53,674,393 | $3,504,797,978 | -$158,066,712 | $65.35 | 401 |
| 2022 Q2 | 54,934,072 | $3,306,541,906 | +$272,946,768 | $60.77 | 399 |
| 2022 Q1 | 48,706,367 | $3,059,113,009 | +$484,420,173 | $62.77 | 406 |
| 2021 Q4 | 41,859,564 | $3,175,408,396 | +$68,797,438 | $75.78 | 417 |
| 2021 Q3 | 39,286,066 | $4,396,724,009 | -$50,803,666 | $111.93 | 458 |
| 2021 Q2 | 40,582,849 | $6,566,058,765 | -$212,966,173 | $161.89 | 489 |
| 2021 Q1 | 43,014,505 | $5,198,663,082 | -$577,210,448 | $121.85 | 431 |
| 2020 Q4 | 47,168,698 | $7,222,583,624 | +$34,959,041 | $153.11 | 391 |
| 2020 Q3 | 47,857,015 | $4,002,705,906 | +$725,073,162 | $83.64 | 296 |
| 2020 Q2 | 37,546,915 | $2,755,741,530 | +$288,178,667 | $73.49 | 259 |
| 2020 Q1 | 35,388,332 | $1,499,800,148 | +$147,459,813 | $42.41 | 239 |
| 2019 Q4 | 31,517,392 | $1,919,496,526 | +$254,964,993 | $60.90 | 242 |
| 2019 Q3 | 27,396,970 | $1,125,805,847 | -$8,940,648 | $40.99 | 173 |
| 2019 Q2 | 27,279,157 | $1,284,603,995 | +$105,162,802 | $47.10 | 174 |
| 2019 Q1 | 25,936,719 | $926,454,784 | +$145,772,798 | $35.72 | 161 |
| 2018 Q4 | 22,072,299 | $630,570,267 | -$52,611,712 | $28.57 | 149 |
| 2018 Q3 | 22,845,520 | $1,008,313,626 | +$171,113,765 | $44.35 | 168 |
| 2018 Q2 | 18,104,948 | $1,063,884,419 | +$2,992,181 | $58.76 | 168 |
| 2018 Q1 | 18,717,431 | $855,351,322 | +$303,920,590 | $45.71 | 131 |
| 2017 Q4 | 12,499,642 | $293,258,607 | +$61,796,870 | $23.48 | 81 |
| 2017 Q3 | 10,043,017 | $179,364,692 | +$6,196,250 | $17.87 | 59 |
| 2017 Q2 | 9,680,933 | $154,895,603 | -$3,830,468 | $16.02 | 33 |
| 2017 Q1 | 9,689,490 | $210,266,458 | -$3,154,774 | $21.76 | 34 |
| 2016 Q4 | 9,833,888 | $197,779,000 | +$197,752,968 | $20.26 | 26 |
| 2016 Q1 | 40 | $1,000 | $0 | $25.00 | 1 |