| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Paradigm Biocapital Advisors LP | 9% | +80% | $84,110,876 | +$37,586,159 | 4,216,084 | +81% | Paradigm BioCapital Advisors LP | 30 Sep 2025 |
| TORONTO DOMINION BANK | 6.9% | $63,650,674 | 3,190,510 | The Toronto-Dominion Bank | 30 Sep 2025 | |||
| MORGAN STANLEY | 5.4% | +180% | $25,231,352 | +$17,597,341 | 2,488,299 | +231% | Morgan Stanley | 30 Jun 2025 |
| MENORA MIVTACHIM HOLDINGS LTD. | 5% | $22,247,279 | 2,303,031 | Menora Mivtachim Holdings Ltd | 11 Mar 2025 | |||
| BlackRock, Inc. | 5% | $23,161,849 | 2,284,206 | BlackRock, Inc. | 30 Jun 2025 | |||
| Soleus Capital Master Fund, L.P. | 4.7% | -6% | $22,155,900 | -$1,419,600 | 2,185,000 | -6% | Soleus Capital Master Fund, L.P. | 30 Jun 2025 |
| Adage Capital Management, L.P. | 2.8% | -60% | $12,335,820 | -$15,949,491 | 1,277,000 | -56% | Adage Capital Management, L.P. | 31 Mar 2025 |
| Monograph Capital Holdings Advisors, LLC | 1.8% | $8,503,556 | 838,615 | Monograph Capital Partners I, L.P. | 05 Jun 2025 |
As of 30 Sep 2025, 158 institutional investors reported holding 43,904,776 shares of UroGen Pharma Ltd. - Ordinary Shares, par value NIS 0.01 per share (URGN). This represents 95% of the company’s total 46,239,275 outstanding shares.
The largest institutional shareholders of UroGen Pharma Ltd. - Ordinary Shares, par value NIS 0.01 per share (URGN) together control 76% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| RTW INVESTMENTS, LP | 9.8% | 4,543,895 | 0% | 1.1% | $90,650,705 |
| Paradigm Biocapital Advisors LP | 9.1% | 4,216,084 | 2.5% | $84,110,876 | |
| TORONTO DOMINION BANK | 6.9% | 3,190,510 | 0% | 0.12% | $63,650,675 |
| BlackRock, Inc. | 5.6% | 2,581,286 | +7.3% | 0% | $51,496,656 |
| MORGAN STANLEY | 5.5% | 2,528,446 | +2% | 0% | $50,442,497 |
| Jefferies Financial Group Inc. | 4.8% | 2,199,652 | 0% | 0.4% | $43,883,057 |
| SILVERARC CAPITAL MANAGEMENT, LLC | 3.4% | 1,577,283 | -22% | 4.6% | $31,466,796 |
| MILLENNIUM MANAGEMENT LLC | 3.2% | 1,468,737 | +147% | 0.02% | $29,301,303 |
| ACORN CAPITAL ADVISORS, LLC | 2.7% | 1,259,749 | 0% | 13% | $25,131,993 |
| SG Americas Securities, LLC | 2.5% | 1,157,383 | +0.72% | 0.08% | $23,090,000 |
| MENORA MIVTACHIM HOLDINGS LTD. | 2.5% | 1,152,531 | 0% | 0.12% | $22,992,993 |
| TANG CAPITAL MANAGEMENT LLC | 2.2% | 1,000,000 | 0% | 0.77% | $19,950,000 |
| D. E. Shaw & Co., Inc. | 1.9% | 888,933 | +3140% | 0.01% | $17,734,213 |
| STATE STREET CORP | 1.8% | 819,446 | +1.5% | 0% | $16,347,948 |
| Migdal Insurance & Financial Holdings Ltd. | 1.7% | 770,909 | 0% | 0.17% | $15,380,000 |
| TCG Crossover Management, LLC | 1.6% | 717,347 | 0.7% | $14,311,073 | |
| ORBIMED ADVISORS LLC | 1.5% | 689,000 | +44% | 0.33% | $13,745,550 |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 1.5% | 687,475 | 0.05% | $13,715,126 | |
| Soleus Capital Management, L.P. | 1.5% | 679,000 | -69% | 0.72% | $13,546,050 |
| CITADEL ADVISORS LLC | 1.3% | 602,277 | +11% | 0.01% | $12,015,426 |
| Boxer Capital Management, LLC | 1.2% | 575,000 | 0% | 3.7% | $11,471,250 |
| JPMORGAN CHASE & CO | 1.2% | 534,545 | +37% | 0% | $10,664,172 |
| Nuveen, LLC | 1.1% | 507,531 | +510% | 0% | $10,125,244 |
| GEODE CAPITAL MANAGEMENT, LLC | 1% | 471,229 | +0.11% | 0% | $9,401,017 |
| GOLDMAN SACHS GROUP INC | 0.92% | 424,916 | +46% | 0% | $8,477,074 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 1,540,403 | $36,075,746 | +$6,412,614 | $23.42 | 5 |
| 2025 Q3 | 43,904,776 | $877,180,389 | +$94,298,897 | $19.95 | 158 |
| 2025 Q2 | 39,798,464 | $545,161,051 | +$3,475,525 | $13.70 | 149 |
| 2025 Q1 | 41,643,932 | $460,619,520 | +$59,835,360 | $11.06 | 139 |
| 2024 Q4 | 36,274,940 | $386,279,169 | -$9,614,096 | $10.65 | 138 |
| 2024 Q3 | 35,097,143 | $445,735,832 | -$58,506,587 | $12.70 | 127 |
| 2024 Q2 | 38,225,503 | $641,423,838 | +$95,777,887 | $16.78 | 115 |
| 2024 Q1 | 625,623 | $9,384,727 | -$5,641,796 | $15.00 | 9 |
| 2023 Q4 | 44,400 | $666,000 | +$222,000 | $15.00 | 2 |
| 2023 Q3 | 17,722,551 | $248,313,866 | +$65,704,033 | $14.01 | 99 |
| 2023 Q2 | 13,209,673 | $136,728,166 | +$7,289,447 | $10.35 | 84 |
| 2023 Q1 | 12,428,895 | $114,822,764 | -$4,573,448 | $9.24 | 64 |
| 2022 Q4 | 13,022,042 | $115,449,037 | -$2,396,478 | $8.87 | 63 |
| 2022 Q3 | 13,274,907 | $110,437,074 | -$658,364 | $8.32 | 55 |
| 2022 Q2 | 13,059,775 | $106,958,080 | -$6,229,150 | $8.19 | 58 |
| 2022 Q1 | 14,184,438 | $123,575,902 | +$1,403,342 | $8.71 | 81 |
| 2021 Q4 | 14,457,812 | $137,523,752 | +$2,034,702 | $9.51 | 68 |
| 2021 Q3 | 14,080,142 | $236,818,324 | +$1,888,037 | $16.82 | 89 |
| 2021 Q2 | 12,068,680 | $184,305,867 | -$6,034,984 | $15.27 | 76 |
| 2021 Q1 | 14,299,733 | $278,499,797 | -$4,155,910 | $19.48 | 88 |
| 2020 Q4 | 14,546,860 | $261,485,580 | -$10,545,671 | $18.02 | 80 |
| 2020 Q3 | 15,009,007 | $288,527,801 | +$6,244,841 | $19.29 | 78 |
| 2020 Q2 | 14,672,947 | $381,998,824 | +$28,259,689 | $26.12 | 83 |
| 2020 Q1 | 13,322,471 | $237,310,555 | -$16,609,336 | $17.84 | 76 |
| 2019 Q4 | 14,182,815 | $472,998,729 | +$4,842,013 | $33.37 | 85 |
| 2019 Q3 | 14,565,627 | $346,783,326 | -$26,214,061 | $23.83 | 82 |
| 2019 Q2 | 14,675,395 | $526,992,234 | +$44,822,103 | $35.94 | 83 |
| 2019 Q1 | 13,453,147 | $496,897,334 | +$142,861,709 | $36.94 | 73 |
| 2018 Q4 | 9,149,141 | $394,154,000 | +$17,909,350 | $43.06 | 62 |
| 2018 Q3 | 9,915,517 | $468,491,000 | +$14,092,486 | $47.23 | 69 |
| 2018 Q2 | 9,602,369 | $482,439,000 | +$24,129,556 | $49.76 | 60 |
| 2018 Q1 | 9,137,601 | $454,036,000 | +$118,577,980 | $49.69 | 43 |
| 2017 Q4 | 6,837,224 | $254,474,000 | +$69,986,832 | $37.21 | 41 |
| 2017 Q3 | 4,604,359 | $144,096,594 | +$1,636,511 | $31.52 | 31 |
| 2017 Q2 | 4,717,110 | $85,193,000 | +$85,192,970 | $18.06 | 20 |