uniQure N.V. - Ordinary Shares, par value 0.05 euro per share (QURE)

Historical Holders from Q1 2014 to Q4 2025

Type / Class: Equity / Ordinary Shares, par value 0.05 euro per share
Symbol: QURE on Nasdaq
Shares outstanding: 61,457,889
Price per share: $23.93
All holders as of 30 Sep 2025: Q3 2025
Total 13F shares as of 30 Sep 2025: 55,358,430
Total reported value: $3,231,722,786
% of total 13F portfolios: 0.01%
Share change: +2,514,888
Value change: +$237,871,227
Avg buy value change: +0.01%
Avg sell value change: -0%
Number of holders: 219
Price from insider filings: $27.30

Reported Shares, Excluding Options vs Price

Reported Value, Excluding Options

Total Investors

Significant Owners of uniQure N.V. - Ordinary Shares, par value 0.05 euro per share (QURE) based on Schedule 13D/G filings

Filer	Ownership	Change %	Holdings Value	Net Change	Nb Shares	Change %	Reporting Name	Report Period
FMR LLC	9.8%		$353,697,322		6,059,574		FMR LLC	30 Sep 2025
RTW INVESTMENTS, LP	7.2%	-24%	$258,285,382	-$42,800,561	4,424,968	-14%	RTW Investments, LP	30 Sep 2025
EcoR1 Capital, LLC	7.5%		$33,269,917		3,632,087		EcoR1 Capital, LLC	10 Dec 2024
Avoro Capital Advisors LLC	6.6%		$57,238,750		3,625,000		Avoro Capital Advisors LLC	30 Jun 2025
Aberdeen Group plc	4.8%	-5%	$171,592,799	+$11,033,623	2,939,743	+6.9%	Aberdeen Group plc	30 Sep 2025
Nantahala Capital Management, LLC	3.8%	-40%	$32,398,743	-$14,687,242	2,051,852	-31%	Nantahala Capital Management, LLC	30 Jun 2025
Vestal Point Capital, LP	0.4%	-91%	$13,133,250	-$202,835,750	225,000	-94%	Vestal Point Capital, LP	30 Sep 2025

As of 30 Sep 2025, uniQure N.V. - Ordinary Shares, par value 0.05 euro per share (QURE) has 219 institutional shareholders filing 13F forms. They hold 55,358,430 shares. of 61,457,889 outstanding shares (90%) .

Top 25 institutional shareholders own 67% of the company.

Filer	Ownership	Nb Shares	Share Change %	Portfolio %	Holdings Value
FMR LLC	9.9%	6,059,574	+412%	0.02%	$353,697,322
Avoro Capital Advisors LLC	7.2%	4,444,444	+23%	3.4%	$259,422,196
RTW INVESTMENTS, LP	7.2%	4,424,968	-14%	3.2%	$258,285,382
EcoR1 Capital, LLC	6.5%	3,988,971	0%	11%	$232,836,237
Aberdeen Group plc	4.8%	2,939,743	+6.9%	0.27%	$171,592,799
FRANKLIN RESOURCES INC	3.2%	1,988,581	+24%	0.03%	$116,073,446
BlackRock, Inc.	2.4%	1,446,099	+8.4%	0%	$84,408,799
STATE STREET CORP	2.3%	1,444,010	+26%	0%	$84,286,864
FRED ALGER MANAGEMENT, LLC	2.1%	1,290,391		0.29%	$75,320,123
JPMORGAN CHASE & CO	1.9%	1,149,351	-36%	0%	$67,087,617
VANGUARD GROUP INC	1.8%	1,125,108	+16%	0%	$65,672,554
683 Capital Management, LLC	1.7%	1,070,000	-17%	5.7%	$62,455,900
Nantahala Capital Management, LLC	1.6%	1,007,492	-51%	3.6%	$58,807,308
JENNISON ASSOCIATES LLC	1.6%	999,484	+614%	0.03%	$58,339,880
PRICE T ROWE ASSOCIATES INC /MD/	1.5%	913,180		0.01%	$53,303,000
TWO SIGMA INVESTMENTS, LP	1.5%	897,538	-4.6%	0.08%	$52,389,293
Eversept Partners, LP	1.4%	877,373		3.9%	$51,212,262
Boxer Capital Management, LLC	1.3%	800,000	-11%	15%	$46,696,000
GEODE CAPITAL MANAGEMENT, LLC	1.2%	721,652	+20%	0%	$42,136,892
GOLDMAN SACHS GROUP INC	1.1%	662,208	+86%	0.01%	$38,653,081
Artia Global Partners LP	1.1%	658,839		6.8%	$38,456,432
Integral Health Asset Management, LLC	0.98%	600,000	-56%	2.6%	$35,022,000
FARALLON CAPITAL MANAGEMENT LLC	0.92%	565,000	+3936%	0.19%	$32,979,050
STEMPOINT CAPITAL LP	0.85%	522,155	-8.8%	6.1%	$30,478,187
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.	0.85%	521,677		2.4%	$30,450,286

Institutional Holders of uniQure N.V. - Ordinary Shares, par value 0.05 euro per share (QURE) across Reporting Periods

Period	Reported Shares, Excl. Options	Value, Excl. Options	Value Change	Puts Notional Value	Calls Notional Value	Price (% of par)	Investors
2025 Q4	671,342	$16,064,892	+$10,722,318			2,392.72%	4
2025 Q3	55,358,430	$3,231,722,786	+$237,871,227	$231,706,629	$221,135,859	5,837%	219
2025 Q2	52,961,222	$738,302,097	+$50,637,545	$17,113,956	$58,468,510	1,394%	143
2025 Q1	49,986,625	$532,054,267	+$84,767,058	$4,602,520	$20,401,672	1,060%	139
2024 Q4	41,605,808	$734,372,507	+$59,578,949	$9,468,580	$41,283,182	1,766%	136
2024 Q3	38,874,270	$192,931,529	+$40,181,239	$2,815,030	$3,811,693	493%	129
2024 Q2	31,728,639	$141,844,153	-$2,897,343	$1,538,432	$5,874,624	448%	114
2024 Q1	32,113,732	$166,994,621	-$35,374,915	$2,898,480	$4,756,960	520%	128
2023 Q4	306,680	$2,076,223	-$92,993			677%	2
2023 Q3	35,395,329	$237,365,107	-$9,124,600	$2,137,806	$4,150,806	671%	157
2023 Q2	35,193,264	$403,167,431	-$113,747,146	$16,806,542	$26,646,919	1,146%	171
2023 Q1	41,381,310	$833,333,752	+$27,830,942	$13,268,023	$28,159,748	2,014%	169
2022 Q4	40,023,295	$907,207,125	-$32,185,443	$11,702,254	$51,902,965	2,267%	170
2022 Q3	41,148,345	$771,699,227	+$17,477,362	$5,869,456	$34,198,396	1,876%	150
2022 Q2	40,344,294	$751,914,385	+$50,482,613	$7,186,984	$40,886,944	1,863.95%	159
2022 Q1	37,798,493	$682,928,536	+$3,923,569	$8,479,782	$27,339,441	1,807%	159
2021 Q4	37,303,093	$773,893,218	-$13,412,909	$15,509,524	$101,022,720	2,074%	162
2021 Q3	36,831,218	$1,179,006,687	+$27,593,714	$17,265,000	$153,071,407	3,200.99%	169
2021 Q2	35,498,122	$1,093,370,577	-$15,980,978	$24,118,000	$141,913,000	3,079.97%	149
2021 Q1	35,943,996	$1,210,948,924	+$63,662,253	$15,378,000	$115,772,200	3,368.97%	152
2020 Q4	33,836,489	$1,222,775,909	-$20,221,121	$19,974,000	$72,650,738	3,613%	157
2020 Q3	35,141,180	$1,290,145,657	-$599,361	$22,082,347	$89,223,010	3,683%	156
2020 Q2	34,387,242	$1,547,367,794	-$18,248,979	$52,146,000	$93,186,000	4,506.01%	169
2020 Q1	35,131,591	$1,666,388,163	-$21,450,767	$40,427,000	$83,209,000	4,745.01%	163
2019 Q4	34,653,130	$2,483,066,359	+$183,700,229	$40,724,000	$119,892,000	7,165.99%	177
2019 Q3	32,037,296	$1,260,861,965	+$155,300,132	$20,281,000	$152,031,000	3,935.98%	152
2019 Q2	26,449,148	$2,066,101,207	+$440,928,247	$75,642,000	$324,346,000	7,815%	141
2019 Q1	22,703,917	$1,354,280,178	+$6,694,373	$14,435,000	$130,766,002	5,965%	127
2018 Q4	22,760,640	$655,512,079	-$4,280,753	$4,384,000	$44,297,000	2,882%	93
2018 Q3	22,571,959	$821,991,896	+$5,903,471	$4,000,000	$76,580,000	3,639%	97
2018 Q2	22,030,252	$832,692,000	+$219,973,383	$2,465,000	$79,202,000	3,779.98%	94
2018 Q1	16,267,232	$382,280,000	+$67,005,770	$1,168,000	$17,097,000	2,350%	66
2017 Q4	13,481,390	$264,111,073	+$105,150,604	$1,955,000	$11,061,000	1,958.98%	59
2017 Q3	7,646,482	$73,374,120	+$459,583			959.99%	33
2017 Q2	7,650,235	$47,354,000	+$3,032,089			618.98%	31
2017 Q1	7,213,508	$41,689,000	-$1,964,408			577.97%	36
2016 Q4	7,619,508	$42,662,000	-$3,166,041		$0	559.94%	50
2016 Q3	7,075,534	$54,129,000	-$7,985,634	$0	$142,000	765.05%	48
2016 Q2	8,046,226	$59,288,000	-$8,285,022	$202,000	$0	736.92%	56
2016 Q1	9,118,016	$108,317,000	+$7,851,286	$241,000	$126,000	1,188%	54
2015 Q4	8,219,077	$135,936,000	-$884,885	$1,830,000	$5,439,000	1,654.02%	64
2015 Q3	7,929,168	$162,145,000	-$249,361	$1,370,000	$7,128,000	2,044.75%	62
2015 Q2	7,678,020	$207,305,000	+$76,361,117	$578,000	$227,000	2,700%	51
2015 Q1	4,924,505	$119,703,000	+$32,406,342			2,431.93%	40
2014 Q4	3,781,705	$56,007,200	+$6,598,220			1,480.97%	25
2014 Q3	3,456,020	$31,869,000	-$65,727			924.31%	26
2014 Q2	3,422,576	$46,512,000	+$44,395			1,359.08%	26
2014 Q1	3,341,209	$51,981,000	+$51,981,041			1,555.42%	24