Janus Henderson Group Plc

13F Holdings History for Structure Therapeutics Inc. - Ordinary Shares, $0.0001 par value (GPCR)

Symbol: GPCR on Nasdaq
Investment type: Equity / Ordinary Shares, $0.0001 par value
Latest Disclosed Ownership: 4.45M shares
Security Ownership: 7.7%

Shares, Excluding Options vs Price

Value, Excluding Options

JANUS HENDERSON GROUP PLC ownership in Structure Therapeutics Inc. Ordinary Shares, $0.0001 par value (GPCR)

2025-11-14 - JANUS HENDERSON GROUP PLC has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 4.45M shares of Structure Therapeutics Inc. Ordinary Shares, $0.0001 par value (GPCR). This represents 7.7% percent ownership of the company. In their previous filing dated 2025-08-14, JANUS HENDERSON GROUP PLC had reported owning 4.57M shares, indicating a decrease of -2.72% percent.

Reporting Name	Ownership %	Change	Value $	Shares owned	Change	Activity %	Price	Form	Report date	Filed at
JANUS HENDERSON GROUP PLC	7.7%	-3.75%	$125M	4.45M	-124,180	-2.72%	$28.00	13G/A	9/30/2025	14 Nov 2025 12:07:22
JANUS HENDERSON GROUP PLC	8%	+5%	$86.1M	4.57M	+217,560	+5%	$18.82	13G/A	6/30/2025	14 Aug 2025 11:26:18
JANUS HENDERSON GROUP PLC	7.6%	+4.29%	$65.5M	4.36M	+195,558	+4.7%	$15.05	13G/A	3/31/2025	14 May 2025 12:32:44
JANUS HENDERSON GROUP PLC	7.3%		$62.6M	4.16M			$15.05	13G/A	12/31/2024	14 Feb 2025 12:22:29

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
9/30/2025	0.06%	0%	$125M	4.45M	-124,180	-2.72%	$28.01	Q3 2025
6/30/2025	0.05%	+0%	$94.9M	4.57M	+217,812	+5%	$20.76	Q2 2025
3/31/2025	0.05%	+0%	$86.1M	4.36M	+195,306		$19.78	Q1 2025
12/31/2024	0.06%	+0%	$113M	4.16M	+203,010	+5.13%	$27.12	Q4 2024
9/30/2024	0.09%	+0.01%	$174M	3.96M	+602,609	+18%	$43.88	Q3 2024
6/30/2024	0.07%	+0.03%	$132M	3.35M	+1,277,569	+61.5%	$39.25	Q2 2024
3/31/2024	0.05%	+0.01%	$89M	2.08M	+532,284	+34.5%	$42.85	Q1 2024
12/31/2023	0.04%	-0.01%	$62.8M	1.54M	-546,907	-26.2%	$40.69	Q4 2023
9/30/2023	0.06%	+0.06%	$97.5M	2.09M	+2,013,893	+2601%	$46.62	Q3 2023
6/30/2023	0%	-0.01%	$3.22M	77.4K	-268,991	-77.6%	$41.57	Q2 2023
3/31/2023	0%	+0%	$3.29M	346K	+346,421	NEW	$9.50^*	Q1 2023

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.