T. Rowe Price Investment Management, Inc.

13F Holdings History for Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)

Symbol: KPTI on Nasdaq
Investment type: Equity / Common Stock, par value $0.0001 per share
Latest Disclosed Ownership: 2.3M shares
Security Ownership: 13.8%

Shares, Excluding Options vs Price

Value, Excluding Options

T. Rowe Price Investment Management, Inc. ownership in Karyopharm Therapeutics Inc. Common Stock, par value $0.0001 per share (KPTI)

2025-11-07 - T. Rowe Price Investment Management, Inc. has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 2.3M shares of Karyopharm Therapeutics Inc. Common Stock, par value $0.0001 per share (KPTI). This represents 13.8% percent ownership of the company. In their previous filing dated 2025-08-14, T. Rowe Price Investment Management, Inc. had reported owning 729K shares, indicating an increase of 216% percent.

Reporting Name	Ownership %	Change	Value $	Shares owned	Change	Activity %	Price	Form	Report date	Filed at
T. Rowe Price Investment Management, Inc.	13.8%	+67.5%	$15.1M	2.3M	+1,575,476	+216%	$6.54	13G/A	10/31/2025	7 Nov 2025 13:02:38
T. Rowe Price Investment Management, Inc.	8.4%		$5.44M	729K			$7.46	13G	6/30/2025	14 Aug 2025 12:12:13

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
9/30/2025	0%	0%	$4.59M	701K	-27,774	-3.81%	$6.54	Q3 2025
6/30/2025	0%	+0%	$3.14M	729K	+589,120	+422%	$4.31	Q2 2025
3/31/2025	0%	+0%	$523K	140K	+139,646	NEW	$3.75	Q1 2025

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.