Brett P. Monia - Oct 6, 2025 Form 4 Insider Report for IONIS PHARMACEUTICALS INC (IONS)

Signature
By: Patrick R. O'Neil, attorney-in-fact For: Brett P. Monia
Stock symbol
IONS
Transactions as of
Oct 6, 2025
Transactions value $
-$30,268
Form type
4
Date filed
10/8/2025, 06:36 PM
Previous filing
Sep 4, 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Monia Brett P Chief Executive Officer, Director 2855 GAZELLE COURT, CARLSBAD By: Patrick R. O'Neil, attorney-in-fact For: Brett P. Monia 2025-10-08 0001537529

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction IONS Common Stock Sale -$30.3K -437 -0.24% $69.26 180K Oct 6, 2025 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on August 13, 2024.