Eric Swayze - Oct 15, 2025 Form 4 Insider Report for IONIS PHARMACEUTICALS INC (IONS)

Role
EVP Research
Signature
By: Patrick R. O'Neil, attorney-in-fact For: Eric Swayze
Stock symbol
IONS
Transactions as of
Oct 15, 2025
Transactions value $
-$3,902
Form type
4
Date filed
10/16/2025, 08:16 PM
Previous filing
Oct 8, 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Swayze Eric EVP Research 2855 GAZELLE COURT, CARLSBAD By: Patrick R. O'Neil, attorney-in-fact For: Eric Swayze 2025-10-16 0001791058

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction IONS Common Stock Options Exercise $0 +125 +67.93% $0.00 309 Oct 15, 2025 by Son F1
transaction IONS Common Stock Sale -$3.9K -53 -17.15% $73.62 256 Oct 16, 2025 by Son F2
holding IONS Common Stock 30.5K Oct 15, 2025 Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction IONS Restricted Stock Unit Options Exercise $0 -125 -20.1% $0.00 497 Oct 15, 2025 Common Stock 125 $0.00 by Son F3, F4
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.
F2 The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice.
F3 Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.
F4 Restricted Stock Units vest in four equal annual installments. Upon vesting, the restricted stock units will be paid out in whole shares of Ionis common stock or cash as may be determined by the Company.