Lawrence Firestone - Nov 10, 2025 Form 4 Insider Report for 22nd Century Group, Inc. (XXII)

Role: Chief Executive Officer, Director
Signature: /s/ Lawrence Firestone by John J. Wolfel, Attorney-in-Fact
Stock symbol: XXII
Transactions as of: Nov 10, 2025
Transactions value $: $0
Form type: 4
Date filed: 11/13/2025, 05:31 PM
Previous filing: Mar 12, 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
FIRESTONE LAWRENCE	Chief Executive Officer, Director	C/O 22ND CENTURY GROUP, INC., 321 FARMINGTON RD., MOCKSVILLE	/s/ Lawrence Firestone by John J. Wolfel, Attorney-in-Fact	2025-11-13	0001112888

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	XXII	Common Stock	Award	$0	+66.8K	+5120.61%	$0.00	68.1K	Nov 10, 2025	Direct	F1, F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	XXII	Stock option (right to buy)	Award	$0	+200K		$0.00	200K	Nov 10, 2025	Common Stock	200K	$1.27	Direct	F3
holding	XXII	Stock option (right to buy)						3.92K	Nov 10, 2025	Common Stock	3.92K	$46.23	Direct	F2, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The restricted stock units vest 1/3 per year on November 10, 2026, 2027 and 2028, subject to continued service with the Company.
F2	The amount shown reflects the number of shares held following the reported transaction, as adjusted for a 1-for-23 stock split effectuated by the issuer on June 20, 2025.
F3	Options vest 1/3 per year on the anniversary of the date of grant, subject to continued service with the Company.