Adage Capital Management, L.P. - Aug 18, 2025 Form 3 Insider Report for Praxis Precision Medicines, Inc. (PRAX)

Role: 10%+ Owner
Signature: /s/ Adage Capital Management, L.P.; By: its general partner Adage Capital Partners LLC; By its managing member Robert Atchinson
Stock symbol: PRAX
Transactions as of: Aug 18, 2025
Transactions value $: $0
Form type: 3
Date filed: 8/19/2025, 04:10 PM
Previous filing: Feb 19, 2025
SEC: View on sec.gov

Reporting Owners (3)

Name	Relationship	Address	Signature	Signature date	CIK
Adage Capital Management, L.P.	10%+ Owner	200 CLARENDON STREET, 52ND FLOOR, BOSTON	/s/ Adage Capital Management, L.P.; By: its general partner Adage Capital Partners LLC; By its managing member Robert Atchinson	2025-08-19	0001535978
Atchinson Robert	10%+ Owner	200 CLARENDON STREET, 52ND FLOOR, BOSTON	/s/ Robert Atchinson	2025-08-19	0001403404
Gross Phillip	10%+ Owner	200 CLARENDON STREET, 52ND FLOOR, BOSTON	/s/ Phillip Gross	2025-08-19	0001403413

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
holding	PRAX	Title of Security (Instr. 4)						2.37M	Aug 18, 2025	See footnotes	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The securities to which this filing relates are held directly by Adage Capital Partners, L.P., a Delaware limited partnership ("ACP"). Adage Capital Management, L.P., a Delaware limited partnership ("ACM"), serves as the investment manager of ACP and as such has discretion over the portfolio securities held by ACP. Robert Atchinson and Phillip Gross are the managing members of (i) Adage Capital Advisors, L.L.C., a Delaware limited liability company, managing member of Adage Capital Partners GP, L.L.C., a Delaware limited liability company, general partner of ACP and (ii) Adage Capital Partners LLC, a Delaware limited liability company, general partner of ACM.
F2	Each of the reporting persons disclaims beneficial ownership of the securities reported herein for purposes of Section 16 of the Securities and Exchange Act of 1934, as amended, except as to such extent of such reporting person's pecuniary interest in the securities, if any.

Content

The securities to which this filing relates are held directly by Adage Capital Partners, L.P., a Delaware limited partnership ("ACP"). Adage Capital Management, L.P., a Delaware limited partnership ("ACM"), serves as the investment manager of ACP and as such has discretion over the portfolio securities held by ACP. Robert Atchinson and Phillip Gross are the managing members of (i) Adage Capital Advisors, L.L.C., a Delaware limited liability company, managing member of Adage Capital Partners GP, L.L.C., a Delaware limited liability company, general partner of ACP and (ii) Adage Capital Partners LLC, a Delaware limited liability company, general partner of ACM.

Each of the reporting persons disclaims beneficial ownership of the securities reported herein for purposes of Section 16 of the Securities and Exchange Act of 1934, as amended, except as to such extent of such reporting person's pecuniary interest in the securities, if any.