| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| BVF PARTNERS L P/IL | Director, Other* | 44 MONTGOMERY ST., 40TH FLOOR, SAN FRANCISCO | BVF Partners L.P., By: BVF Inc., its general partner, By: /s/ Mark N. Lampert, President | 2025-06-13 | 0001055947 |
| BIOTECHNOLOGY VALUE FUND L P | Director, Other* | 44 MONTGOMERY ST., 40TH FLOOR, SAN FRANCISCO | Biotechnology Value Fund, L.P., By: BVF I GP LLC, its general partner, By: /s/ Mark N. Lampert, Chief Executive Officer | 2025-06-13 | 0000918923 |
| BVF I GP LLC | Director, Other* | 44 MONTGOMERY ST., 40TH FLOOR, SAN FRANCISCO | BVF I GP LLC, By: /s/ Mark N. Lampert, Chief Executive Officer | 2025-06-13 | 0001803805 |
| BIOTECHNOLOGY VALUE FUND II LP | Director, Other* | 44 MONTGOMERY ST., 40TH FLOOR, SAN FRANCISCO | Biotechnology Value Fund II, L.P., By: BVF II GP LLC, its general partner, By: /s/ Mark N. Lampert, Chief Executive Officer | 2025-06-13 | 0001102444 |
| BVF II GP LLC | Director, Other* | 44 MONTGOMERY ST., 40TH FLOOR, SAN FRANCISCO | BVF II GP LLC, By: /s/ Mark N. Lampert, Chief Executive Officer | 2025-06-13 | 0001803806 |
| Biotechnology Value Trading Fund OS LP | Director, Other* | P.O. BOX 309 UGLAND HOUSE, GRAND CAYMAN, CAYMAN ISLANDS | BVF Partners OS Ltd., By: BVF Partners L.P., its sole member, By: BVF Inc., its general partner, By: /s/ Mark N. Lampert, President | 2025-06-13 | 0001660683 |
| BVF Partners OS Ltd. | Director, Other* | P.O. BOX 309 UGLAND HOUSE, GRAND CAYMAN, CAYMAN ISLANDS | Biotechnology Value Trading Fund OS LP, By: BVF Partners L.P., its investment manager, BVF Inc., its general partner, By: /s/ Mark N. Lampert, President | 2025-06-13 | 0001660684 |
| BVF GP HOLDINGS LLC | Director, Other* | 44 MONTGOMERY ST., 40TH FLOOR, SAN FRANCISCO | BVF GP Holdings LLC, By: /s/ Mark N. Lampert, Chief Executive Officer | 2025-06-13 | 0001803809 |
| BVF INC/IL | Director, Other* | 44 MONTGOMERY ST., 40TH FLOOR, SAN FRANCISCO | BVF Inc., By: /s/ Mark N. Lampert, President | 2025-06-13 | 0001056807 |
| LAMPERT MARK N | Director, Other* | 44 MONTGOMERY ST., 40TH FLOOR, SAN FRANCISCO | /s/ Mark N. Lampert | 2025-06-13 | 0001233840 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| holding | OLMA | Common stock, $0.0001 par value | 2.66M | Jun 11, 2025 | Direct | F1, F2 | |||||
| holding | OLMA | Common stock, $0.0001 par value | 2M | Jun 11, 2025 | Direct | F1, F3 | |||||
| holding | OLMA | Common stock, $0.0001 par value | 348K | Jun 11, 2025 | Direct | F1, F4 | |||||
| holding | OLMA | Common stock, $0.0001 par value | 99.6K | Jun 11, 2025 | See footnote | F1, F5 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | OLMA | Stock Option (Right to buy) | Award | $0 | +24.2K | $0.00 | 24.2K | Jun 11, 2025 | Common stock, $0.0001 par value | 24.2K | $4.08 | See footnote | F7, F9 | |
| holding | OLMA | Pre-Funded Warrant | 3.29M | Jun 11, 2025 | Common stock, $0.0001 par value | 3.29M | $0.00 | Direct | F1, F2, F6 | |||||
| holding | OLMA | Pre-Funded Warrant | 2.63M | Jun 11, 2025 | Common stock, $0.0001 par value | 2.63M | $0.00 | Direct | F1, F3, F6 | |||||
| holding | OLMA | Pre-Funded Warrant | 336K | Jun 11, 2025 | Common stock, $0.0001 par value | 336K | $0.00 | Direct | F1, F4, F6 | |||||
| holding | OLMA | Stock Option (Right to buy) | 23K | Jun 11, 2025 | Common stock, $0.0001 par value | 23K | $12.36 | See footnote | F7, F8 | |||||
| holding | OLMA | Stock Option (Right to buy) | 21.5K | Jun 11, 2025 | Common stock, $0.0001 par value | 21.5K | $7.84 | See footnote | F7, F8 | |||||
| holding | OLMA | Stock Option (Right to buy) | 21.5K | Jun 11, 2025 | Common stock, $0.0001 par value | 21.5K | $3.61 | See footnote | F7, F8 | |||||
| holding | OLMA | Stock Option (Right to buy) | 21.5K | Jun 11, 2025 | Common stock, $0.0001 par value | 21.5K | $27.66 | See footnote | F7, F8 | |||||
| holding | OLMA | Stock Option (Right to buy) | 21.5K | Jun 11, 2025 | Common stock, $0.0001 par value | 21.5K | $19.00 | See footnote | F7, F8 | |||||
| holding | OLMA | Stock Option (Right to buy) | 21.5K | Jun 11, 2025 | Common stock, $0.0001 par value | 21.5K | $19.00 | See footnote | F7, F8 | |||||
| holding | OLMA | Stock Option (Right to buy) | 21.5K | Jun 11, 2025 | Common stock, $0.0001 par value | 21.5K | $19.00 | See footnote | F7, F8 |
| Id | Content |
|---|---|
| F1 | This Form 4 is filed jointly by Biotechnology Value Fund, L.P. ("BVF"), Biotechnology Value Fund II, L.P. ("BVF2"), Biotechnology Value Trading Fund OS LP ("Trading Fund OS"), BVF Partners OS Ltd. ("Partners OS"), BVF I GP LLC ("BVF GP"), BVF II GP LLC ("BVF2 GP"), BVF GP Holdings LLC ("BVF GPH"), BVF Partners L.P. ("Partners"), BVF Inc. and Mark N. Lampert (collectively, the "Reporting Persons"). Each of the Reporting Persons is a member of a Section 13(d) group with respect to the Issuer's outstanding shares of Common Stock. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein except to the extent of his or its pecuniary interest therein. |
| F2 | Securities owned directly by BVF. As the general partner of BVF, BVF GP may be deemed to beneficially own the securities owned directly by BVF. As the sole member of BVF GP, BVF GPH may be deemed to beneficially own the securities owned directly by BVF. As the investment manager of BVF, Partners may be deemed to beneficially own the securities owned directly by BVF. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by BVF. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by BVF. |
| F3 | Securities owned directly by BVF2. As the general partner of BVF2, BVF2 GP may be deemed to beneficially own the securities owned directly by BVF2. As the sole member of BVF2 GP, BVF GPH may be deemed to beneficially own the securities owned directly by BVF2. As the investment manager of BVF2, Partners may be deemed to beneficially own the securities owned directly by BVF2. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by BVF2. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by BVF2. |
| F4 | Securities owned directly by Trading Fund OS. As the general partner of Trading Fund OS, Partners OS may be deemed to beneficially own the securities owned directly by Trading Fund OS. As the investment manager of Trading Fund OS and the sole member of Partners OS, Partners may be deemed to beneficially own the securities owned directly by Trading Fund OS. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by Trading Fund OS. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by Trading Fund OS. |
| F5 | Securities held in a certain Partners managed account (the "Partners Managed Account"). Partners may be deemed to have indirect beneficial ownership of the securities of the Issuer held by the Partners Managed Account for purposes of Rule 16a-1(a)(2) because the securities account for more than 10% of the market value of the portfolio of the Partners Managed Account as of the reporting date. Partners, as the investment manager of the Partners Managed Account, may be deemed to beneficially own the securities held by the Partners Managed Account. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities held by the Partners Managed Account. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities held by the Partners Managed Account. |
| F6 | Each Pre-Funded Warrant may be exercised for one share of Common Stock. The Pre-Funded Warrants are exercisable immediately after the issue date and may be exercised at any time until all of the Pre-Funded Warrants are exercised in full. A holder of Pre-Funded Warrants (together with its affiliates and other attribution parties) may not exercise any portion of a Pre-Funded Warrant to the extent that immediately prior to or after giving effect to such exercise the holder would own more than 9.99% of the shares of Common Stock outstanding immediately after exercise. |
| F7 | Partners, BVF Inc. and Mr. Lampert may be deemed to have a pecuniary interest in the securities reported owned herein due to a certain agreement between Partners and Gorjan Hrustanovic, who serves on the Issuer's board of directors and as a member of Partners, pursuant to which Dr. Hrustanovic is obligated to transfer the economic benefit, if any, received upon the sale of the shares issuable upon exercise of the securities reported owned herein to Partners. As such, Dr. Hrustanovic disclaims beneficial ownership of the securities reported herein except to the extent of his pecuniary interest therein. |
| F8 | The shares subject to the option have fully vested. |
| F9 | The shares subject to the option vest in a series of 12 successive equal monthly installments measured from June 11, 2025, subject to Dr. Hrustanovic's continuous service through each applicable vesting date. Such shares vest in full on the date of the Issuer's next annual meeting of stockholders if such stock option is not otherwise fully vested by such date, subject to Dr. Hrustanovic's continuous service through such vesting date. |
For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each of the Reporting Persons may be deemed to be a director by deputization of the Issuer due to a member of Partners, Gorjan Hrustanovic, serving on the Board of Directors of the Issuer, and his agreement to transfer the economic benefit, if any, received upon the sale of the shares issuable upon exercise of the securities reported owned herein to Partners.