EcoR1 Capital, LLC - Mar 31, 2025 Form 4 Insider Report for Zymeworks Inc. (ZYME)

Signature
/s/ Oleg Nodelman, Individually and as Manager of EcoR1 Capital, LLC
Stock symbol
ZYME
Transactions as of
Mar 31, 2025
Transactions value $
$1,497,322
Form type
4
Date filed
4/2/2025, 07:02 PM
Previous filing
Mar 27, 2025
Next filing
Apr 7, 2025

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction ZYME Common Stock Purchase $51.7K +4.4K +0.03% $11.75 17.3M Mar 31, 2025 See Note F1, F2, F3
transaction ZYME Common Stock Purchase $565K +48.7K +0.28% $11.60 17.3M Apr 1, 2025 See Note F1, F4, F5
transaction ZYME Common Stock Purchase $881K +74.4K +0.43% $11.85 17.4M Apr 2, 2025 See Note F1, F6, F7
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 The reporting persons are EcoR1 Capital, LLC ("EcoR1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the "Funds"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein.
F2 Qualified Fund purchased 4,129 of the shares purchased in this transaction.
F3 After this transaction, Qualified Fund held 16,178,745 shares of the Issuer's Common Stock.
F4 Qualified Fund purchased 45,622 of the shares purchased in this transaction.
F5 After this transaction, Qualified Fund held 16,224,367 shares of the Issuer's Common Stock.
F6 Qualified Fund purchased 69,720 of the shares purchased in this transaction.
F7 After this transaction, Qualified Fund held 16,294,087 shares of the Issuer's Common Stock.

Remarks:

Mr. Nodelman is a director of the Issuer. Scott Platshon, an employee of EcoR1, also serves as a director of the Issuer and was nominated for the board by EcoR1 and the Funds.