MICHAEL GRAY - 06 Feb 2025 Form 4 Insider Report for Upstream Bio, Inc. (UPB)

Signature
/s/ Allison Ambrose, Attorney-in-Fact
Issuer symbol
UPB
Transactions as of
06 Feb 2025
Transactions value $
$0
Form type
4
Filing time
07 Feb 2025, 17:31:01 UTC
Previous filing
10 Oct 2024

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction UPB Stock Option (Right to Buy) Award $0 +195K $0.00 195K 06 Feb 2025 Common Stock 195K $8.53 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 The shares underlying this option shall vest in forty-eight equal monthly installments following February 6, 2025, subject to the Reporting Person's continued service on each such vesting date.

Remarks:

Exhibit 24.2 - Substitute Power of Attorney