Everett Rand Sutherland - Feb 6, 2025 Form 4 Insider Report for Upstream Bio, Inc. (UPB)

Signature
/s/ Allison Ambrose, Attorney-in-Fact
Stock symbol
UPB
Transactions as of
Feb 6, 2025
Transactions value $
$0
Form type
4
Date filed
2/7/2025, 05:32 PM
Previous filing
Oct 10, 2024

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction UPB Stock Option (Right to Buy) Award $0 +500K $0.00 500K Feb 6, 2025 Common Stock 500K $8.53 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 The shares underlying this option shall vest in forty-eight equal monthly installments following February 6, 2025, subject to the Reporting Person's continued service on each such vesting date.

Remarks:

Exhibit 24.2 - Substitute Power of Attorney