Julianne Bruno - Mar 20, 2025 Form 4 Insider Report for CRISPR Therapeutics AG (CRSP)

Role: Chief Operating Officer
Signature: Elizabeth Ryland Waldinger, attorney-in-fact
Stock symbol: CRSP
Transactions as of: Mar 20, 2025
Transactions value $: -$70,668
Form type: 4
Date filed: 3/24/2025, 05:35 PM
Previous filing: Mar 18, 2025
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	CRSP	Common Shares	Options Exercise		+3.75K	+44.08%		12.3K	Mar 20, 2025	Direct	F1
transaction	CRSP	Common Shares	Sale	-$70.7K	-1.71K	-13.98%	$41.23	10.5K	Mar 21, 2025	Direct	F2
holding	CRSP	Common Shares						7.09K	Mar 20, 2025	The Julianne Bruno 2022 GRAT

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	CRSP	Restricted Stock Units	Options Exercise		-3.75K	-25%		11.3K	Mar 20, 2025	Common Shares	3.75K		Direct	F1, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit represents a contingent right to receive one share of CRSP Common Shares.
F2	Amount reported represents the number of shares required to be sold by the reporting person to cover the tax withholding obligation in connection with the vesting of these restricted stock units. This sale is mandated by the Company's RSU Settlement Policy to fund the tax withholding obligation and does not represent a discretionary trade by the reporting person.
F3	This restricted stock unit award was granted on March 20, 2024 with respect to 15,000 Common Shares, with (i) one quarter of the shares vesting on March 20, 2025, (ii) one quarter of the shares vesting on March 20, 2026, (iii) one quarter of the shares vesting on March 20, 2027, and (iv) one quarter of the shares vesting on March 20, 2028.