Stephen Michael Rothenberg - May 29, 2025 Form 4 Insider Report for Tyra Biosciences, Inc. (TYRA)

Role: Director
Signature: /s/ Ali D. Fawaz, Attorney-in-Fact
Stock symbol: TYRA
Transactions as of: May 29, 2025
Transactions value $: $0
Form type: 4
Date filed: 6/2/2025, 04:05 PM
Previous filing: May 9, 2024
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Rothenberg Stephen Michael	Director	C/O TYRA BIOSCIENCES, INC., 2656 STATE STREET, CARLSBAD	/s/ Ali D. Fawaz, Attorney-in-Fact	2025-06-02	0002022747

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	TYRA	Stock Option (Right to Buy)	Award	$0	+22.2K		$0.00	22.2K	May 29, 2025	Common Stock	22.2K	$9.25	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The option was granted pursuant to the Issuer's Non-Employee Director Compensation Program. 1/12th of the total number of shares of common stock subject to the option vest monthly following May 29, 2025, the date of grant. In the event the next occurring annual meeting of the Issuer's stockholders occurs prior to the first anniversary of the date of grant, any remaining unvested portion of the option will vest on the date of such annual meeting of the Issuer's stockholders, subject to the Reporting Person's continuous service to the Issuer through each vesting date.

Content

The option was granted pursuant to the Issuer's Non-Employee Director Compensation Program. 1/12th of the total number of shares of common stock subject to the option vest monthly following May 29, 2025, the date of grant. In the event the next occurring annual meeting of the Issuer's stockholders occurs prior to the first anniversary of the date of grant, any remaining unvested portion of the option will vest on the date of such annual meeting of the Issuer's stockholders, subject to the Reporting Person's continuous service to the Issuer through each vesting date.