| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| BROWN JAMES E | President & CEO, Director | C/O DURECT CORPORATION, 10240 BUBB ROAD, CUPERTINO | /s/ James E. Brown | 15 Jul 2025 | 0001134620 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | DRRX | Common Stock | Award | $0 | +96,959 | +55% | $0.000000 | 273,412 | 11 Jul 2025 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). 100% of the RSUs shall vest on the one-year anniversary of the Grant Date, subject to the Employee's continued service with the Company or any affiliate on such vesting date. |