Uwe Klein - 07 Aug 2025 Form 4 Insider Report for Septerna, Inc. (SEPN)

Signature
/s/ Ran Xiao, Attorney-in-Fact
Issuer symbol
SEPN
Transactions as of
07 Aug 2025
Net transactions value
$0
Form type
4
Filing time
11 Aug 2025, 19:01:56 UTC
Previous filing
24 Oct 2024
Next filing
19 Aug 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Klein Uwe SVP, Biological Sciences C/O SEPTERNA, INC., 250 EAST GRAND AVENUE, SOUTH SAN FRANCISCO /s/ Ran Xiao, Attorney-in-Fact 11 Aug 2025 0002040350

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction SEPN Stock Option (Right to Buy) Award $0 +30,000 $0.000000 30,000 07 Aug 2025 Common Stock 30,000 $11.70 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 1/48th of the shares subject to such option shall vest and become exercisable in substantially equal monthly installments on each monthly anniversary of August 1, 2025, subject to the Reporting Person's continuous service to the Issuer on each such date.