An van Es-Johansson - 13 Aug 2025 Form 4 Insider Report for PLUS THERAPEUTICS, INC. (PSTV)

Role: Director
Signature: /s/ Andrew Sims, attorney-in-fact
Issuer symbol: PSTV
Transactions as of: 13 Aug 2025
Net transactions value: $0
Form type: 4
Filing time: 15 Aug 2025, 16:29:04 UTC
Previous filing: 20 Feb 2025
Next filing: 11 Dec 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
van Es-Johansson An	Director	C/O PLUS THERAPEUTICS INC., 4200 MARATHON BOULEVARD, SUITE 200, AUSTIN	/s/ Andrew Sims, attorney-in-fact	15 Aug 2025	0001795902

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	PSTV	Stock Option (Right to Buy)	Award	$0	+297,794		$0.000000	297,794	13 Aug 2025	Common Stock	297,794	$0.5744	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The options vest monthly over 12 months from the Grant Date in substantially equal monthly installments, provided that the options vest in full on the Issuer's 2026 Annual Stockholder Meeting, subject to the Reporting Person's continued service to the Issuer through each applicable vesting date or, if earlier, such annual meeting.