| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Mahadevia Ankit | Director | C/O SPERO THERAPEUTICS, INC., 675 MASSACHUSETTS AVENUE, 14TH FLOOR, CAMBRIDGE | /s/ Maegan Deare, Attorney-in-Fact for Ankit Mahadevia | 2025-09-02 | 0001720974 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | SPRO | Common Stock | Sale | -$12.9K | -6.57K | -0.93% | $1.97 | 703K | Aug 28, 2025 | Direct | F1, F2 |
| Id | Content |
|---|---|
| F1 | The reported transaction is a sale of common stock effected to cover tax withholding obligations pursuant to a "sell to cover" provision included in each RSU Agreement in connection with the vesting of restricted stock unit ("RSUs") that were granted to the Reporting Person on August 26, 2021. |
| F2 | Amount includes 65,817 shares of common stock held by the Mahadevia-Mehta Family Trust, of which the Reporting Person is a trustee. |