| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Papp Timothy M. | Chief Financial Officer | C/O DURECT CORPORATION, 10240 BUBB ROAD, CUPERTINO | /s/ Timothy M. Papp | 08 Sep 2025 | 0001935786 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | DRRX | Common Stock | Options Exercise | $143K | +110K | +34.2% | $1.30 | 432K | 08 Sep 2025 | Direct |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | DRRX | Stock Option (right to buy) | Options Exercise | $0 | -110K | -100% | $0.00 | 0 | 08 Sep 2025 | Common Stock | 110K | $1.30 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | The option will vest and become exercisable in installments of one-sixteenth (1/16) of the total number of shares at the end of each three-month period following the grant date, subject to the Reporting Person providing continuous service to the Issuer through the applicable vesting date. |