John Oyler - Nov 11, 2025 Form 4 Insider Report for BeOne Medicines Ltd. (ONC)

Signature
/s/ Qing Nian, as Attorney-in-Fact
Stock symbol
ONC
Transactions as of
Nov 11, 2025
Transactions value $
$0
Form type
4
Date filed
11/13/2025, 05:06 PM
Previous filing
Sep 18, 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
OYLER JOHN Chief Executive Officer, Director C/O BEONE MEDICINES I GMBH, AESCHENGRABEN 27, 21ST FLOOR, BASEL, SWITZERLAND /s/ Qing Nian, as Attorney-in-Fact 2025-11-13 0001042047

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction ONC Ordinary Shares Gift $0 -151K -2.03% $0.00 7.3M Nov 11, 2025 Direct F1
transaction ONC Ordinary Shares Gift $0 -859K -11.76% $0.00 6.44M Nov 12, 2025 Direct F1
holding ONC Ordinary Shares 482K Nov 11, 2025 See Footnote F2
holding ONC Ordinary Shares 7.72M Nov 11, 2025 See Footnote F3
holding ONC Ordinary Shares 28.2M Nov 11, 2025 See Footnote F4
holding ONC Ordinary Shares 9.55M Nov 11, 2025 See Footnote F5
holding ONC Ordinary Shares 102K Nov 11, 2025 See Footnote F6
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Bona fide gift of shares to a private foundation which is exempt from Section 16(b) of the Securities Exchange Act pursuant to Rule 16b-5.
F2 These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership.
F3 These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.
F4 These securities are held by Oyler Investment LLC, of which 99% of the the limited liability company interest owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.
F5 These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account.
F6 These securities are held by The John Oyler Legacy Trust for the benefit of the Reporting Person's minor child, for which the Reporting Person disclaims beneficial ownership.