Wendell Wierenga - Oct 27, 2025 Form 4 Insider Report for CYTOKINETICS INC (CYTK)

Role
Director
Signature
/s/ John O. Faurescu, attorney-in-fact for Dr. Wierenga
Stock symbol
CYTK
Transactions as of
Oct 27, 2025
Transactions value $
-$212,975
Form type
4
Date filed
10/27/2025, 05:59 PM
Previous filing
Oct 21, 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
WIERENGA WENDELL Director 350 OYSTER POINT BLVD, SOUTH SAN FRANCISCO /s/ John O. Faurescu, attorney-in-fact for Dr. Wierenga 2025-10-27 0001239956

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction CYTK Common Stock Options Exercise $43.8K +4.38K +13.48% $10.00 36.8K Oct 27, 2025 Direct
transaction CYTK Common Stock Sale -$257K -4.38K -11.88% $58.68 32.4K Oct 27, 2025 Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction CYTK Non-Qualified Stock Option (Right to Buy) Options Exercise $0 -4.38K -100% $0.00 0 Oct 27, 2025 Common Stock 4.38K $10.00 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 This option shall vest and become exercisable as to 4,375 shares divided into equal monthly installments such that the option shall be 100% vested on January 4, 2017.