Edward M. MD Kaye - Dec 1, 2025 Form 4 Insider Report for CYTOKINETICS INC (CYTK)

Role
Director
Signature
/s/ John Faurescu, attorney-in-fact for Dr. Kaye
Stock symbol
CYTK
Transactions as of
Dec 1, 2025
Transactions value $
-$1,487,436
Form type
4
Date filed
12/2/2025, 09:18 AM
Previous filing
Nov 12, 2025
Next filing
Dec 5, 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Kaye Edward M. MD Director 350 OYSTER POINT BLVD, SOUTH SAN FRANCISCO /s/ John Faurescu, attorney-in-fact for Dr. Kaye 2025-12-02 0001522780

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction CYTK Common Stock Options Exercise $100K +8.06K +80.83% $12.40 18K Dec 1, 2025 Direct
transaction CYTK Common Stock Options Exercise $285K +20K +110.86% $14.25 38K Dec 1, 2025 Direct
transaction CYTK Common Stock Sale -$1.87M -28.1K -73.77% $66.72 9.98K Dec 1, 2025 Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction CYTK Non-Qualified Stock Option (Right to Buy) Options Exercise $0 -8.06K -100% $0.00 0 Dec 1, 2025 Common Stock 8.06K $12.40 Direct F1
transaction CYTK Non-Qualified Stock Option (Right to Buy) Options Exercise $0 -20K -100% $0.00 0 Dec 1, 2025 Common Stock 20K $14.25 Direct F2
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 This option shall vest and become exercisable as to 8,064 shares divided into equal monthly installments such that the option shall be 100% vested on January 3, 2018.
F2 This option shall vest and become exercisable in 12 equal monthly installments and shall become fully vested on May 18, 2018.