ARCH Venture Partners IX, LLC - Jul 25, 2025 Form 4 Insider Report for Lyell Immunopharma, Inc. (LYEL)

Role
10%+ Owner
Signature
ARCH Venture Partners IX, LLC, By: /s/ Mark McDonnell, as Attorney-in-Fact for Robert Nelsen, Managing Director
Stock symbol
LYEL
Transactions as of
Jul 25, 2025
Transactions value $
$0
Form type
4
Date filed
7/29/2025, 09:25 PM
Previous filing
Sep 7, 2022

Reporting Owners (8)

Name Relationship Address Signature Signature date CIK
ARCH Venture Partners IX, LLC 10%+ Owner 8755 W. HIGGINS ROAD, SUITE 1025, CHICAGO ARCH Venture Partners IX, LLC, By: /s/ Mark McDonnell, as Attorney-in-Fact for Robert Nelsen, Managing Director 2025-07-29 0001723174
ARCH Venture Partners IX, L.P. 10%+ Owner 8755 W. HIGGINS ROAD, SUITE 1025, CHICAGO ARCH Venture Partners IX, L.P., By: ARCH Venture Partners IX, LLC, its General Partner, By: /s/ Mark McDonnell, as Attorney-in-Fact for Keith Crandell, Managing Director 2025-07-29 0001723173
ARCH Venture Partners IX Overage, L.P. 10%+ Owner 8755 W. HIGGINS ROAD, SUITE 1025, CHICAGO ARCH Venture Partners IX Overage, L.P., By: ARCH Venture Partners IX, LLC, its General Partner, By: /s/ Mark McDonnell, as Attorney-in-Fact for Keith Crandell, Managing Director 2025-07-29 0001723172
ARCH Venture Fund IX, L.P. 10%+ Owner 8755 W. HIGGINS ROAD, SUITE 1025, CHICAGO ARCH Venture Fund IX, L.P., By: ARCH Venture Partners IX, L.P., its General Partner, By: ARCH Venture Partners IX, LLC, its General Partner, By: /s/ Mark McDonnell, as Attorney-in-Fact for Keith Crandell, Managing Director 2025-07-29 0001666306
ARCH Venture Fund IX Overage, L.P. 10%+ Owner 8755 W. HIGGINS ROAD, SUITE 1025, CHICAGO ARCH Venture Fund IX Overage, L.P., By: ARCH Venture Partners IX Overage, L.P., its General Partner, By: ARCH Venture Partners IX, LLC, its General Partner, By: /s/ Mark McDonnell, as Attorney-in-Fact for Keith Crandell, Managing Director 2025-07-29 0001666307
CRANDELL KEITH 10%+ Owner C/O ARCH VENTURE PARTNERS IX, LLC, 8755 W. HIGGINS ROAD, SUITE 1025, CHICAGO Keith Crandell, Managing Director, By: /s/ Mark McDonnell, as Attorney-in-Fact 2025-07-29 0001219039
BYBEE CLINTON 10%+ Owner C/O ARCH VENTURE PARTNERS IX, LLC, 8755 W. HIGGINS ROAD, SUITE 1025, CHICAGO Clinton Bybee, Managing Director, By: /s/ Mark McDonnell, as Attorney-in-Fact 2025-07-29 0001219043
NELSEN ROBERT 10%+ Owner 8755 W. HIGGINS ROAD, SUITE 1025, CHICAGO Robert Nelsen, Managing Director, By: /s/ Mark McDonnell, as Attorney-in-Fact 2025-07-29 0001219042

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
holding LYEL Common Stock 910K Jul 25, 2025 By ARCH Venture Fund IX, L.P. F1, F3
holding LYEL Common Stock 910K Jul 25, 2025 By ARCH Venture Fund IX Overage, L.P. F2, F3
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 These shares are directly held by ARCH Venture Fund IX, L.P. ("ARCH IX"). ARCH Venture Partners IX, L.P. ("GPLP"), as the sole general partner of ARCH IX, may be deemed to beneficially own the shares held by ARCH IX. ARCH Venture Partners IX, LLC ("GPLLC"), as the sole general partner of GPLP, may be deemed to beneficially own the shares held by ARCH IX. As managing directors of GPLLC, each of Keith Crandell, Robert Nelsen and Clinton Bybee (the "ARCH Managing Directors"), may be deemed to beneficially own the shares held by ARCH IX. Each of GPLP, GPLLC and the ARCH Managing Directors disclaims beneficial ownership of the securities reported herein, except to the extent of their pecuniary interest therein, if any.
F2 These shares are directly held by ARCH Venture Fund IX Overage, L.P. ("ARCH Overage"). ARCH Venture Partners IX Overage, L.P. ("Overage GPLP"), as the sole general partner of ARCH Overage, may be deemed to beneficially own the shares held by ARCH Overage. GPLLC, as the sole general partner of Overage GPLP, may be deemed to beneficially own the shares held by ARCH Overage. As managing directors of GPLLC, each of the ARCH Managing Directors may be deemed to beneficially own the shares held by ARCH Overage. Each of Overage GPLP, GPLLC and the ARCH Managing Directors disclaims beneficial ownership of the securities reported herein, except to the extent of their pecuniary interest therein, if any.
F3 The amount of shares reported herein reflects a 1-for-20 reverse stock split that occurred on May 27, 2025.

Remarks:

Due to overlapping managing directors, a separate Form 3 was filed for the purchase of common stock of Lyell by ARCH Venture Fund XIII, L.P., and related entities: ARCH Venture Partners XIII, L.P., ARCH Venture Partners XIII, LLC, Steven Gillis, Kristina Burow and Paul Berns.