Brian J. Brille - Jun 18, 2025 Form 4 Insider Report for Caris Life Sciences, Inc. (CAI)

Role: Vice Chairman and Executive Vice President, Director
Signature: /s/ J. Russel Denton, Attorney-in-Fact
Stock symbol: CAI
Transactions as of: Jun 18, 2025
Transactions value $: $630,000
Form type: 4
Date filed: 6/23/2025, 06:30 PM
Previous filing: Jun 17, 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Brille Brian J	Vice Chairman and Executive Vice President, Director	C/O CARIS LIFE SCIENCES, INC., 750 W. JOHN CARPENTER FREEWAY, SUITE 800, IRVING	/s/ J. Russel Denton, Attorney-in-Fact	2025-06-23	0002071959

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	CAI	Common Stock	Award	$0	+132K		$0.00	132K	Jun 18, 2025	Direct	F1
transaction	CAI	Common Stock	Purchase	$630K	+30K	+22.65%	$21.00	162K	Jun 20, 2025	Direct
holding	CAI	Common Stock						500K	Jun 18, 2025	By Trusts	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents an award of restricted stock units which vest in accordance with the applicable grant agreement.
F2	The Reporting Person disclaims beneficial ownership except to the extent of his pecuniary interest therein.

Remarks:

Vice Chairman and Executive Vice President